etc

  1. haidut

    Stress/Injury (mitochondrial dysfunction) sufficient to cause de-differentiation, even cancer

    One of the most pernicious myths in medicine is the "irreversibility" of several cellular processes related to aging, diabetes, fibrosis and, of course, cancer. Perhaps the most fundamental of those processes is cellular differentiation. To this day, the dominant opinion in medicine is that once...
    • haidut
    • Thread
    • cancer differentiation electron flow etc mitochondria oxphos reactive oxygen species ros
    • Replies: 2
    • Forum: Scientific Studies
  2. haidut

    Pregnenolone (P5) improves recovery from stroke

    One of the few direct studies with P5 in-vivo, though that may be changing as I noticed the rate of articles on P5 has been rising over the last 5-6 years. This study used four (4) administrations of P5, at a HED of just 0.3mg/kg, 1, 6, 12, and 18 hours after the (ischemic) stroke was caused...
    • haidut
    • Thread
    • cognition etc ischemia mitochondria p5 pregnenolone strength stroke
    • Replies: 1
    • Forum: Scientific Studies
  3. haidut

    Reductive stress drives pathogenesis and progression of tuberculosis

    I am posting this study b/c it is one of the few I have seen lately demonstrating that even infectious diseases are metabolic in origin. Of course, a pathogen is involved as well, but as it turns out it may not be able to cause an infection by itself. For that to happen, a metabolic dysfunction...
    • haidut
    • Thread
    • etc infection inflammation oxphos ros tnf-a tuberculosis
    • Replies: 0
    • Forum: Scientific Studies
  4. haidut

    Restoring oxidative metabolism has curative effects on cancer (leukemia)

    A great study, which directly demonstrates not only the OXPHOS deficiency characteristic of all "cancer" cells, but also proving that restoration of OXPHOS is highly therapeutic (and likely curative) for leukemia. Just as importantly, the study demonstrates that cancer cells have, in fact...
  5. haidut

    COVID-19 is an energy deficiency disease

    Yet another seemingly non-metabolic disease turns out to be nothing but energy deficiency in disguise. Apparently, the SARS-CoV-2 virus selectively disables so-called complex I of the electron transport chain (ETC), and as such the overall OXPHOS process. Such inhibition is known to reliably...
    • haidut
    • Thread
    • complex i covid-19 electron transport chain energy etc mitochondria oxphos sars-cov-2
    • Replies: 5
    • Forum: Scientific Studies
  6. haidut

    Loss of mitochondrial function (OXPHOS) induces de-differentiation (cancer)

    The study only focuses on the lymphatic system and its cells, but the principle is general and has been observed in other organ/tissue cells. The most obvious example is cancer - no matter which organ it occurs in, the tumor is composed of de-differentiated cells not unlike the stem cells from...
    • haidut
    • Thread
    • cancer differentiation electron transport chain etc loss metabolism mitochondria oxphos
    • Replies: 0
    • Forum: Scientific Studies
  7. haidut

    Inhibiting respiration/metabolism reliably causes bipolar disorder

    Just a quick post on a study, which claims to have established a reliable method for inducing bipolar disorder in an animal model. This reliable method consists simply of administering a low-dose of a mitochondrial inhibitor. More specifically, an inhibitor of complex I of the electron transport...
    • haidut
    • Thread
    • bipolar disorder depression etc mania metabolism mitochondria oxphos
    • Replies: 0
    • Forum: Scientific Studies
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