mast cell

  1. AlphaCog

    Histamine secretion induced by N-acetyl cysteine

    Abstract The mucolytic drug N-acetyl cysteine has been shown to release histamine from cultured mouse mast cells and from human basophils. At neutral pH the release was moderate and non-cytotoxic. If the acidity of the drug was not neutralized, this histamine release was markedly potentiated...
  2. haidut

    Serotonin (5-HT) is a key driver of asthma

    Yet another blow to the status of the so-called "happiness hormone". While histamine, acetylcholine, and estrogen have long been known as key drivers of asthma the link between the mast cells and the nervous system's production of the vasoconstrictor acetylcholine has remained unknown. The study...
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