Need advice for uterine / cervical fibroid treatment plan

[messylttlfoodie]

Hi, I've been trying to get some advice on this issue a few times now and no luck yet, so let me try this again.

Today I saw an NHS gynae specialist for what is suspected to be a fibroid growing from inside my uterus / cervix and protruding out from cervical canal. I thought it was a polyp but as it's hard like muscle not soft, she thinks it's a fibroid, that it looks very benign but she wants to do a hysteroscopy next.

She mentioned that I would be given a drug to "relax me" - I didn't manage to write down the name and can't remember but from my research I think she was talking about the likes of Cytotec or misoprostol to relax my cervix. She warned me that I may experience period like cramps after the insertion of the saline, and that I may want to take some ibuprofen or paracetamol 1 hour prior.

She also said that if it's too painful we can stop, that I can have a local anaesthetic or even be put under (I want to avoid anaesthesia though). She was honestly great, I felt very reassured and very lucky after having read some horror stories on how women are treated sometimes when it comes to gynaecological issues and pain management.

One thing I'll say is that when she examined me today, and grabbed the fibroid and asked me if I felt any pain, I didn't feel a thing, I didn't even feel her grab it, it was weird.

Now, I just came across some info @haidut posted about vitamin D preventing and even reversing uterine fibroids, along with Progesterone.
I'm just playing around with different ideas now and want to see what options I might have. Thing is, this fibroid - if it is in fact a fibroid - isn't just sitting inside my uterine walls like the images I've come across, it's growing and protruding from inside my cervix, has a smooth and deep red/purplish appearance, and is changing position throughout my cycle ie protruding more after ovulation and then retracting after my period.

My last two periods since I noticed this growth have been super heavy to the point of near fainting (anemia?) and spotting, bleeding and unpleasant discharge between periods - really not fun. Other than that I have no other symptoms.

So I have a few questions bouncing around in my head:

1) Should I go ahead with the hysteroscopy
2) What should I expect, has anyone here had one and what was your experience (especially on the NHS / in UK)
3) Thoughts on the cervix relaxing drugs I mentioned? Painkillers?
4) Vitamin D supplementation?
5) Progest-E
6) Should I get a full blood test to check my levels before supplementing those?
7) Any other advice?

My main concerns are basically pain of the procedure, medications and treatments offered by them and alternative treatments I might consider.

Hope someone can help

 

[oxphoser]

If it were me, I’d start taking vitamin D as one of the things you do. As I understand it, unless you live at the equator and spend a lot of time in the sun, humans have to supplement it. At some point, get it tested even if you have to pay for the test yourself.

Here’s another study where it says:

“Leiomyomas (ie fibroids) size in vitamin D group significantly decreased as

compared to placebo group.”

The effect of vitamin D supplementation on the size of uterine leiomyoma in women with vitamin D deficiency - PubMed

Our results showed that administration of vit D3 may reduce the size of leiomyoma. It seems that vitamin D administration is the effective way to treat leiomyoma.

pubmed.ncbi.nlm.nih.gov

 

[aliml]

Yet another big win for vitamin D, much to the chagrin of the medical establishment, which has been throwing "mud" (read: fake, ghostwritten studies) against vitamin D ever since it showed so much promise in human studies for both preventing and treating COVID-19. Now, the study below demonstrates yet another serious condition where vitamin D may be able to both "prevent and treat". Namely, the dreaded uterine fibroids, which affect 80%+ of women at least once in their lifetime, and the rates of which continue to increase. In other words, a disease that affects virtually all women, and for which the only available "treatments" are surgery and/or even radiation. Some doctors prescribe synthetic progestins, but those have demonstrated an unacceptable level of side effects, too high for even medicine's increased tolerance for homicidal interventions. As such, the synthetic progestins are not widely used as treatment. On top of that, those treatments are not only dangerous, but they do not resolve the condition as the fibroids invariably reoccur after a few years. What's worse, these fibroids have a high chance of turning into uterine/endometrial cancer, so an effective prevention/treatment would be a huge win for public health. Well, based on the study below, it looks like humble vitamin D may be able to fit the bill. Keeping its blood levels above 20ng/mL may have a significant preventive effects and a level above 30ng/mL may even shrink/remove the fibroids. Btw, since I mentioned the synthetic progestins and it is accepted that progestins have beneficial effects, using bioidentical progesterone may be another viable treatment option but without the side effect risks of synthetic progestins. Finally, multiple studies have demonstrated synergism between vitamin D and bioidentical progesterone, allowing for much lower doses of each to be used when taken together. So, a combo of low-dose vitamin D and bioidentical progesterone may very well be the "killer combo" mainstream medicine has been looking for and dares not discuss in public out of fear the sales of surgeries, radiation treatments and synthetic progestins will collapse for good.

Redirecting
High Vitamin D levels prevent development and growth of fibroids, finds study

"...Uterine fibroids are noncancerous tumors of the myometrium that cause significant morbidity including menorrhagia and pelvic pain, often requiring medical or surgical intervention. Fibroid treatments that have few side-effects and can preserve fertility are a clinical priority of all treating doctors. A new study conducted by Quaker E Harman and team showed that high levels of vitamin D prevent fibroid growth, although their effects are constrained by the small number of individuals with blood 25(OH)D levels below ≥30ng/mL. Further as compared with existing medical and surgical treatments for fibroids that have significant side-effects and impact fertility, vitamin D is safe and compatible with pregnancy. The findings of the study were published in Fertility and Sterility.Clinical priorities include fibroids therapies that can sustain fertility and have minimal adverse effects. In order to evaluate the relationship between serum vitamin D and uterine fibroid development, incidence, and loss, this study was carried out. The purpose of this prospective population cohort research (enrollment 2010–2012) was to test 25-hydroxyvitamin D (25(OH)D), perform standardized ultrasounds, and update variables based on the Detroit, Michigan region. There were four study visits spread over five years. Self-identified African American or Black women between the ages of 23 and 35 who had not previously received a clinical diagnosis of fibroids participated in this study. Using immunoassay or liquid chromatography-tandem mass spectrometry, serum 25(OH)D was analyzed for this investigation. The main results were fibroid incidence and fibroid growth, as determined by change in log volume every 18 months. Estimated volume differences for high and low 25(OH)D were derived using adjusted growth estimates from linear mixed models. Age-specific Cox regression was used to estimate hazard ratios for incidence differences. Using Poisson regression, the secondary outcome of fibroid loss (decrease in fibroid number between visits) was predicted. The 25(OH)D was treated as a time-varying component, together with covariates (reproductive and hormonal characteristics, demographics, body mass index, and current smoking).The key findings of this study were:1. At enrolment, 73% of the 1,610 individuals had insufficient vitamin D (<ng/mL), and just 7% had sufficient vitamin D (≥30ng/mL), with a mean age of 29.2 years. 2. Similar to the minimum adjusted result of -8.4%, serum 25(OH)D >20ng/mL compared with <20ng/mL was linked to an estimated 9.7% reduction in fibroid development. 3. A rough 22% reduction in incidence was linked to serum 25(OH)D levels below ≥30ng/mL when compared to levels over >30ng/mL, which is close to the unadjusted estimate of 0.84. 4. Additionally, fibroid reduction increased by 32% in the group with >30ng/mL. In conclusion, concentrations of 25(OH)D greater than 20 ng/mL were linked to slower fibroid development. Results of research that looked at 25(OH)D concentrations >30 ng/mL suggested that fibroid removal was more likely and that the incidence of fibroid growth may have decreased."

Regression of fibroids in a number of organs has been extensively documented in older studies using androgens. Those studies led to the development and approval of the DHT-based steroid Drostanolone for women with not only breast cancer but all kinds of other fibroid issues. Drostanolone retains its FDA approval to this day but most doctors do not know about it. Anyways, the benefit of androgens was proven to be through opposition of estrogens. And yes, both prevention AND reversal of fibroids were seen in those older studies. So, anything that opposes estrogen will likely have beneficial effects including aspirin, vitamin E, pregnenolone, etc. Progesterone is probably safer for women than androgens but sometimes a combination of progesterone + androgen works even better. Lack of DHEA is a big issue in older women and giving them DHEA or testosterone has been shown to help with many fibrotic conditions and of course cancer. You may want to ask your doctor about something like bromocriptine or another anti-serotonin drug like cyproheptadine as those can greatly amplify the anti-estrogen effects of progesterone and have been shown to also benefit fibrotic conditions by blocking 5-HT2B.
LSD-derivatives Like Bromocriptine Can Fully Cure Breast Cancer
Cyproheptadine Is An Estrogen Antagonist, May Treat Breast Cancer
The Serotonin Receptor 5-HT2B Is Required For Cancer; Can Be Blocked

12 Natural Remedies for Fibroids

Natural remedies for fibroids include apple cider vinegar, blackstrap molasses, castor oil packs and important dietary changes.

earthclinic.com

 

[Lindama707]

My situation was different, but you may find parts useful.

My gyn was great... she was a bit crusty and practical. I had fibroids for about 5-6 yrs. After I got over the shock, I didn't do anything. I had regular ultra sound to watch. I had no pain but periods could be heavy with clots. I was not willing to get the standard hysterectomy. My gyn sent me to a doc ready to retire to check, who she said would not panic and imagine cancer like the younger ones might .... he told me I was not a cancer candidate and time went on. One day, I woke up and decided to do the surgery, Myomectomy, take fibroids not uterus. All along, my fibroids, in the uterus, were the size of a 20 week pregnancy. My family was alarmed, I was not. My gyn rightly suggested that I go to a surgeon who "made their money saving uteruses"... by that time the technology was there. I went to a fertility doc who said "no problem". Things went well. He was a good surgeon who left me with a small bikini scar. Some of my friends had long incisions over the abdomen. I had the surgery and recovered.... that was 1994. I have not been back to any docs since. Since then, before internet, I have read about systemic enzymes possibly helping. I would probably approach it differently next time. Would also have explored anabolic/catabolic dynamics more.

A few extra details. For me, there was a psycho/spiritual piece. I was in my 40s, no children, there was a period of grief around that. they woke me up in OR and I saw my Kids/fibroids all clean on a tray... and I was in the maternity wing after surgery. I never had physical children, but... I also was fortunate to have a spinal anesthetic because my mother had a serious reaction to surgical anesthetics... it helped me to recover faster. The surgeon was surprised to see how radiant I was the next morning.

Best wishes on your journey!

 

[belcanto]

I knew someone who had uterine fibroids and i recommended high-vitamin fish oil at the time. This was before I discovered Ray Peat, so my recommendation now would be optimal amounts of Vitamin A and Vitamin D. At least give this a shot before doing a myomectomy. So many of us are deficient in Vitamin D.

 

[messylttlfoodie]

I knew someone who had uterine fibroids and i recommended high-vitamin fish oil at the time. This was before I discovered Ray Peat, so my recommendation now would be optimal amounts of Vitamin A and Vitamin D. At least give this a shot before doing a myomectomy. So many of us are deficient in Vitamin D.

Thank you! What would you say would be optional amounts of A and D since the RDA isn't always right and I'm wondering about targets for treating specific conditions

 

[sunny]

Maybe you might read something here that would help you decide on a coarse of action. Estrogen, Uterine Fibroids, and Thyroid Nodules – Functional Performance Systems (FPS)

 

[messylttlfoodie]

Does anyone know if this is any good to take for fibroids? Apparently I need to take 7000IU per day.
This one below says "Each liquid drop contains 1,400 IU of Vitamin D3 and 25mcg of Vitamin K (as MK-7), the form of K2 with the highest bioavailability. In addition, our liquid base includes MCT oil which has many benefits including enhanced metabolism and improved energy levels."

MAX Absorption Vitamin D3 + K2 (MK-7) Liquid Drops with MCT Oil, Naturally Unflavored

https://www.amazon.co.uk/dp/B09HN2PJQD/

In order to get 7000IU per day I'd have to take 5 drops, but then I'd get 125mcg K2 alongside, and I don't know if that's a good thing?

Reason I ask is because I already have this and would prefer not having to buy yet another supplement....

Also my Cronometer shows I get enough vitamin A from dairy, but should should I supplement extra retinol in order to treat fibroids?

 

[sunny]

Peat transcript from interviews in this thread.

Does Blocking Estrogen Cause Spontaneous Expulsion Of Fibroids?/necrotic Tissue Etc

During a CAT scan I had recently, it was discovered that I have several large uterine fibroids and my uterus is the size of a 5 month pregnancy. Normally the treatments are a. estrogen and progesterone blockers, b. embolization or removal of a fibroid, and c. hysterectomy. For the number and...

raypeatforum.com