Hey fam!
I've been doing some deep dive into Trehalose, and this stuff is blowing me away.
What is Trehalose: a crystalline disaccharide C12H22O11 that is found in various organisms (as fungi and insects), Trehalose is about half as sweet as sucrose, and is sometimes used as a sweetener in commercially prepared foods.
Over time scientist have found a way to extract Trehalose from Plant Life. It tastes just like sugar yet it doesn’t act like sugar. Your body breaks it down differently, it’s actually healthy.
Many of the processed foods or frozen foods like freezy pops for children have Trehalose as the sweetener. Trehalose is more conducive to heat and cold temperatures than table sugar.
What we understand from the science of Glycomics that cells communicate through sugar and proteins. Sugars are the (OS) operating system of the body. There are eight sugars found on the planet we call them Glyconutrients.
What makes Trehalose so special is that it acts like a sugar but it’s not really a sugar like good old fashioned table sugar. It’s a Disaccharide. Trehalose also has the added advantage of being an antioxidant
Trehalose is thought to form into a gel phase as cells dehydrate, which prevents disruption of internal cell organelles, by effectively splinting them in position. Rehydration then allows normal cellular activity to be resumed without the major, lethal damage that would normally follow a dehydration/rehydration cycle. Trehalose is also present in the nutrition exchange liquid of hornets and their larvae. Trehalose is the major carbohydrate energy storage molecule used by insects for flight. One possible reason for this is that the glycosidic linkage of trehalose, when acted upon by an insect trehalase, releases two molecules of glucose, which is required for the rapid energy requirements of flight. This is double the efficiency of traditional Glucose. As you know athletes love Glucose for energy. If insects us Trehalose for flight because it has double the energy of Glucose what do you think Treahlose can do for athletes?
Our data indicated that a daily intake of 10 g of trehalose improved glucose tolerance and progress to insulin resistance. Furthermore, these results suggested that trehalose can potentially reduce the development of metabolic syndrome and associated lifestyle-related diseases, such as type 2 diabetes. - Daily Intake of Trehalose Is Effective in the Prevention of Lifestyle-Related Diseases in Individuals with Risk Factors for Metabolic Syndrome - PubMed
Diabetes mellitus is the most prevalent metabolic disorder contributing to significant morbidity and mortality in humans. Many preventative and therapeutic agents have been developed for normalizing glycemic profile in patients with diabetes. In addition to various pharmacologic strategies, many non-pharmacological agents have also been suggested to improve glycemic control in patients with diabetes. Trehalose is a naturally occurring disaccharide which is not synthesized in human but is widely used in food industries. Some studies have provided evidence indicating that it can potentially modulate glucose metabolism and help to stabilize glucose homeostasis in patients with diabetes. Studies have shown that trehalose can significantly modulate insulin sensitivity via at least 7 molecular pathways leading to better control of hyperglycemia. In the current study, we concluded about possible anti-hyperglycemic effects of trehalose suggesting trehalose as a potentially potent non-pharmacological agent for the management of diabetes.
Affiliations expand
I've been doing some deep dive into Trehalose, and this stuff is blowing me away.
What is Trehalose: a crystalline disaccharide C12H22O11 that is found in various organisms (as fungi and insects), Trehalose is about half as sweet as sucrose, and is sometimes used as a sweetener in commercially prepared foods.
Over time scientist have found a way to extract Trehalose from Plant Life. It tastes just like sugar yet it doesn’t act like sugar. Your body breaks it down differently, it’s actually healthy.
Many of the processed foods or frozen foods like freezy pops for children have Trehalose as the sweetener. Trehalose is more conducive to heat and cold temperatures than table sugar.
What we understand from the science of Glycomics that cells communicate through sugar and proteins. Sugars are the (OS) operating system of the body. There are eight sugars found on the planet we call them Glyconutrients.
Trehalose is thought to form into a gel phase as cells dehydrate, which prevents disruption of internal cell organelles, by effectively splinting them in position. Rehydration then allows normal cellular activity to be resumed without the major, lethal damage that would normally follow a dehydration/rehydration cycle. Trehalose is also present in the nutrition exchange liquid of hornets and their larvae. Trehalose is the major carbohydrate energy storage molecule used by insects for flight. One possible reason for this is that the glycosidic linkage of trehalose, when acted upon by an insect trehalase, releases two molecules of glucose, which is required for the rapid energy requirements of flight. This is double the efficiency of traditional Glucose. As you know athletes love Glucose for energy. If insects us Trehalose for flight because it has double the energy of Glucose what do you think Treahlose can do for athletes?
Because Trehalose protects the cells from extreme temperature changes by hydrating the cells it acts as an age reverser or beauty enhancer for several cosmetic manufacturers. There is no question that Trehalose protects the cells from stress.
Scientists have found that Trehalose
Improves Sustained Energy
Improves Cellular Hydration
Improves Brain Function
Enhances Memory
Stimulates Calcium Absorption
Regulates Insulin and Glucose Levels in obese men.
Enhances cellular communication
Lowers body odor
So what does one do with Trehalose?
You could treat it like sugar and replace white table sugar with Trehalose.
You could drop a teaspoon or two of Trehalose in your coffee and tea or in your daily smoothie to sweeten it up.
It looks like sugar and it sure does taste like sugar.
That’s why we call it the sugar with a conscience.
Scientists have found that Trehalose
Improves Sustained Energy
Improves Cellular Hydration
Improves Brain Function
Enhances Memory
Stimulates Calcium Absorption
Regulates Insulin and Glucose Levels in obese men.
Enhances cellular communication
Lowers body odor
So what does one do with Trehalose?
You could treat it like sugar and replace white table sugar with Trehalose.
You could drop a teaspoon or two of Trehalose in your coffee and tea or in your daily smoothie to sweeten it up.
It looks like sugar and it sure does taste like sugar.
That’s why we call it the sugar with a conscience.
Disaccharide | Unit 1 | Unit 2 | Bond |
Sucrose (table sugar, cane sugar, beet sugar, or saccharose) | Glucose | Fructose | α(1→2)β |
Lactulose | Galactose | Fructose | β(1→4) |
Lactose (milk sugar) | Galactose | Glucose | β(1→4) |
Maltose | Glucose | Glucose | α(1→4) |
Trehalose | Glucose | Glucose | α(1→1)α |
Cellobiose | Glucose | Glucose | β(1→4) |
Diabetes mellitus is the most prevalent metabolic disorder contributing to significant morbidity and mortality in humans. Many preventative and therapeutic agents have been developed for normalizing glycemic profile in patients with diabetes. In addition to various pharmacologic strategies, many non-pharmacological agents have also been suggested to improve glycemic control in patients with diabetes. Trehalose is a naturally occurring disaccharide which is not synthesized in human but is widely used in food industries. Some studies have provided evidence indicating that it can potentially modulate glucose metabolism and help to stabilize glucose homeostasis in patients with diabetes. Studies have shown that trehalose can significantly modulate insulin sensitivity via at least 7 molecular pathways leading to better control of hyperglycemia. In the current study, we concluded about possible anti-hyperglycemic effects of trehalose suggesting trehalose as a potentially potent non-pharmacological agent for the management of diabetes.
Autophagy induction by trehalose: Molecular mechanisms and therapeutic impacts
Kiana Hosseinpour-Moghaddam 1, Michele Caraglia 2, Amirhossein Sahebkar 3 4 5Affiliations expand
- PMID: 29663416
- DOI: 10.1002/jcp.26583