Omega-3 To Treat PTSD. Had to Stop the Study

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j.

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Possible deleterious effects of adjanctive omega-3 fatty acids in post-traumatic stress disorder patients

Since anger and hostility are frequently pivotal problem behaviors in post-traumatic stress disorder (PTSD) patients and depression is a common comorbid feature of PTSD, we initiated a preliminary open trial of dietary supplementation with capsules of fish oil rich in eicosapentaenoic acid (EPA) in a group of PTSD patients with these problems. Our purpose in the present study was to examine whether EPA-rich fish oil has any effect on the symptoms of PTSD patients, especially those related to depression, anger, and hostility.

We found that we had to severely curtail the study in response to complaints by our patients, which we feel are worthy of reporting here, in spite of the open-label nature and the very small number of participants.

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burtlancast

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Ray right again.
 
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One man who “felt no change” and thus refused to continue and one woman who complained of “feeling greasy all over”. Only these two people dropped out, they didn't have to stop the study.
 

Hugh Johnson

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Such_Saturation said:
One man who “felt no change” and thus refused to continue and one woman who complained of “feeling greasy all over”. Only these two people dropped out, they didn't have to stop the study.

"The subject group consisted of three men and three women,"

If you lose one third of your subjects to negative effects you do have to interrupt the study. The survivorship bias alone will ruin the study. Of course, a better question is to ask why would you even form a study with just 6 participants.
 
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I have the feeling at least one of them was an M.D. turned "researcher".
 

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