Hydergine Prevents Alcohol-induced Life-span, Locomotor, And Lipofuscin Accumulation Reduction

DaveFoster

Member
Joined
Jul 23, 2015
Messages
5,027
Location
Portland, Oregon
Pharmacology. 1978;16 Suppl 1:36-44.
Dihydroergotoxine(Hydergine) and ethanol-induced aging of C57BL/6J male mice.
Samorajski T, Rolsten C, Pratte KA.
The residual effects of dihydroergotoxine (Hydergine), ethanol, and
Hydergine-plus-ethanol were investigated in old male mice of the C57BL/6J strain.
Prolonged 10% v/v ethanol, concomitant with adequate nutrition, produced a
significant decrease in life-span, decreased spontaneous locomotor activity and
reduced lipofuscin accumulation in neurons of the reticularis gigantocellularis.
These effects were not apparent in mice treated with Hydergine or alcohol
combined with Hydergine.


I found this in the Ray Peat E-mail Depository thread. This is very interesting and demonstrates the neuro-protective effect of hydergine for those who engage in alcohol consumption and alludes to even further neuronal benefits to chronic consumption of the substance. Dosing is something that needs to be investigated.
 
Back
Top Bottom