Project 2 ( FULL): AUTOIMMUNE AND MOVEMENT DISORDERS

burtlancast

Member
Joined
Jan 1, 2013
Messages
3,263
To save yourself some serious time during transcribing, please first visit this short updated FAQ : http://www.raypeatforum.com/forum/viewtopic.php?f=78&t=5168 (this FAQ was last updated on: 9 nov)

Post here to claim a part for you to transcribe, and it will be yours. Check further down this thread to see which parts remain to be trancribed.

You can transcribe multiple parts; but in order to facilitate the attribution process for verifying , please avoid transcribing adjacents parts ( ex: do parts 1 and 3 instead of parts 1 and 2)


Please don't forget to EDIT YOUR INITIAL POST and include BOTH TRANSCRIBED and VERIFIED parts. This will keep localized inside the thread each volunteer's work.

Each of your post should include thus at least these 3 lines:
-Part 1 for Burt
- Link for transcribed part 1: https://mega.co.nz/#!EQpFBSci_ZdN_ ... WDN356wsbY
- Link for verification of part 2: https://mega.co.nz/#!EQQwci_ZdN_ ... WDN356wsbY

Once the parts have been verified, no more work is needed from anyone. The final piecing together of all parts into a full transcript will be done by Loess.

Only post here to claim a part and to upload your finished files.
Comments can be posted at: http://www.raypeatforum.com/forum/viewtopic.php?f=78&t=5165

Lenght: 57.15 min
Name: Politics and Science- Ray Peat - Autoimmune and Movement Disorders 2012
Download link: download/file.php?id=241

Part 1: for dd99 https://mega.co.nz/#!lQoEFB4S!HJI0YX7eY ... qjZoJAMCQI
Part 2: by Burtlancast https://mega.co.nz/#!BdAUnb6R!eOavn_EtN ... fPbu6ukrNI
Part 3: for arinryan https://mega.co.nz/#!Ico2QKxL!CMZTW-c36 ... Y_2zKeqIwU
Part 4: for arinryan https://mega.co.nz/#!wV4X3JDA!FHhkys_a2 ... 85V6ElpOc4
Part 5: for Sheila https://mega.co.nz/#!IQAHFbxa!TBtVlTaQc ... TLkIrftyzI
Part 6: for Sheila https://mega.co.nz/#!dVBSiKbL!n_hdaE8lQ ... 6Eiefdl9Os
Part 7: for Loess https://mega.co.nz/#!YJZCEBzT!qbZIkjpYR ... kBohDmMX9w
Part 8: for Loess https://mega.co.nz/#!AARHmY5Y!STu6iETss ... YOCE7I7mLM
Part 9: for dd99 https://mega.co.nz/#!lNRG1QRY!-P0FQx7gN ... Lv-B9m6HMw
Part 10: for Kiran https://mega.co.nz/#!BZgi2Z7b!T4yAg0S0N ... yFB24ZUKsc

PS: part 6 is 10 minutes long: Ray couldn't stop talking....() ;)

In case there's a problem with a download link, here's a backup download link containing a zipped file with all 10 parts: http://ul.to/t165a9wh
 

juanitacarlos

Member
Joined
Dec 31, 2012
Messages
417
Re: Transcript project 2: Autoimmune and Movement Disorders

I will do Part 1 and Part 2.
 

arinryan

Member
Joined
Mar 1, 2014
Messages
47
Re: Transcript project 2: Autoimmune and Movement Disorders

I will do part 3 and part 4, glad to help! where is that coffee emoticon? ah ha :coffee
 

Sheila

Member
Joined
Nov 6, 2014
Messages
374
Re: Transcript project 2: Autoimmune and Movement Disorders

I will do 5 & 6, thank you.
 

loess

Member
Joined
Sep 22, 2013
Messages
390
Re: Transcript project 2: Autoimmune and Movement Disorders

I'll take parts 7 and 8
dt880smile.png
 

Sheila

Member
Joined
Nov 6, 2014
Messages
374
Re: Transcript project 2: Autoimmune and Movement Disorders

Part 5

Interviewer: So, let's use an example of one of these diseases, like multiple sclerosis, the myelin sheath for some, unknown reason, according to the medical
authorities, becomes worn away or taken away and the nerves stop functioning and people start having trouble with motor control; they say it's caused by inflammation,
how does that relate to your idea.

Dr Peat: Anything that causes a lack of energy will cause tissue to swell up, take up water and as it swells up the tissue tries to renew itself. Cells are
always renewing themselves in a tremendous churning process of taking down the old stuff and putting up new stuff. For example someone said that during the night
I think it was 60% of our molecules in our brain, the fat substance, consists a big part of the brain, 60% of them are totally resynthesised every night.

And just an hour after death, a massive amount of the brain substance has decomposed because it isn't constantly being reconstituted so you have to think in terms of a
healthy stable organism as being in extremely intense turnover processes and so if you cut off the energy supply, the first thing that happens is the cell
takes up water and that excites the restorative process to run faster but if it takes up more and more water that shifts the whole direction and the cells at a
certain stage of excitation will de-differentiate and try to turn into a stem cell to grow new tissue as a healing process and if there's even less energy, then that process stops.

When you have just a chronic, slight energy deprivation, you get a chronic slight oedema and that oedema, one of the things that happens is that the myelin swells
up and whilst being taken down it isn't being resynthesised efficiently. Thyroid, progesterone, pregnenolone and saturated fatty acids are things that support the reforming of the myelin.
And when the energy is down for example, thyroid is low, then you can't make the pregnenolone and progesterone and so you just can't synthesise it as fast as it is being taken down.

Interviewer: So it's really, it's a condition when you're put under stress and you don't have the energy resources to keep rebuilding yourself under that stress.

Dr Peat: Yeah, and it's just remarkably similar in the processes in the degenerative brain diseases of aging or the development of cancer or of deforming arthritis.
Inflammation, chronic inflammation like pancreatitis, hepatitis, chronic kidney disease and so on, all the same processes are involved just in different proportions
of energy supply and irritation or stimulation.

Interviewer: Is that the that Szent-gyorgyi referred to as the condition of being sick?

Dr Peat : Ah yeah, no that was Hans Seyle.

Interviewer: Oh that was Hans Seyle, thank you, and that's just a shortage of energy basically.

Dr Peat: Yeah, I think that's the gap between stimulation and energy resources, it's used to define excitotoxicity that kills brain cells but it's really the same process
in your pancreas or kidney or skin, anywhere exactly the same energy systems, slight differences in the particular proteins, like in Huntingdon's disease for example there's
that polyglutamine repeat that accumulates, but it's really just a symptom of an inflammatory state with a particular history that leads to that being a problem.
But the fact that it usually waits until you are 40 years old means that things like rheumatoid arthritis or Chron's disease or any of these chronic inflammatory things, they
almost never develop in little kids; it takes a while and being exposed to certain environments for each kind of thing to develop. But there are a few common factors
in the organism or its environment that are involved in almost all of these: Alzheimers, Parkinson's disease, Lou Gehrig's disease, Huntingdon's, various nervous-dementia diseases.

Interviewer: MS?

Dr Peat: Yeah, and the skeletal, nervous, inflammatory - diabetes even, involves inflammation and the failure to regenerate properly the beta cells. [Beta cells] are being killed
in the same way as brain cells are being killed basically. Instead of making insulin as the cells are renewed, the cells are killed as fast as they are renewed so they stop making insulin.
But if you stop killing them they can start making insulin again. The same with the brain, if you stop killing the brain it's always in a process of repair and regeneration.

I might have mentioned a man with ALS that I talked to about 8 or 10 years ago; 70 years old and he'd had all the best neurologists examine him and he absolutely was convinced he had
Lou Gerhig's disease and he was declining the same as other people he met in the neurology offices and he decided to start doing things to stop inflammation and support repair
and he did them consistently for a few months whilst still declining but then he stopped declining and within a few months was repaired. It was less than a year the whole process
and people he had met in the neurology offices where they had the same rate of decline were totally disabled by the time he was totally well.
 

dd99

Member
Joined
Apr 26, 2014
Messages
434
OP
burtlancast

burtlancast

Member
Joined
Jan 1, 2013
Messages
3,263
Re: Transcript project 2: Autoimmune and Movement Disorders

I've updated the FAQ to clarify how the checking process takes place when someone transcribes adjacents parts.
 

Sheila

Member
Joined
Nov 6, 2014
Messages
374
Re: Transcript project 2: Autoimmune and Movement Disorders

Part 6

Interviewer: That's impressive, so one of the things you've talked about in terms of helping your body rebuild from conditions like this is basically a very simple thing, just keeping your blood sugar up; maybe you can describe what happens when somebody is low on blood sugar - reading you talking about what happens, basically this catabolic effect that happens in your body just from low blood sugar to my mind is pretty
convincing about how important it is to keep your blood sugar up.

Dr Peat: Yes. The first thing when your blood sugar falls because your liver hasn't stored enough glycogen to turn into glucose, the first reaction is for adrenalin to increase to try to squeeze more glycogen into your circulation, for your brain primarily and when the glycogen is absolutely gone, the adrenalin keeps activating the breakdown of fat and provides increased amounts of circulating fats to make up for the lack of sugar but, after the fat becomes a source of energy, your cells still need some sugar to maintain their basic processes so they turn protein into sugar and to do that they increase cortisol which breaks down muscle, skin, thymus glands - thymus is the first to go. And the cortisol will eat up your muscle and skin and immune system pretty quickly to feed your heart, lungs and brain to keep them alive. So every time your
blood sugar falls you're shifting over to fat metabolism and breaking down protein so that your muscles are one of the places that store glycogen so as your muscles get smaller then more burden is put on your liver to keep your blood sugar steady and that makes your liver progressively suffer and eventually it gets to the point that your brain isn't getting either the right energy or the right kind of energy.

One of the things that happens with aging, is that we progressively from the time we are born, at birth, we're very highly saturated in our fats because they've been formed from glucose in utero and we can only make saturated, mono-unsaturated and omega-9 unsaturated fats when we're supplied with either sugar or protein. But once we start eating in the ordinary environment, our tissues start loading up on the polyunsaturateds from the environment, and by the time a person is 40, the brain is pretty full of either the
arachadonic acid series or, if they have eaten a lot of fish, there will be mostly the long highly unsaturated fats, mostly the DHA type of fish-oil derived omega-3 fats and even with a pretty average diet, the old person's brain is very highly biased towards the DHA type fats and if you look at Parkinson's Disease, their favourite genetic protein, that some people like to say is the cause of Parkinson's Disease, synuclein - is the Parkinson's equivalent of glutamine repeat ???of Huntingdon's or the amyloid or tore??? fibrils of
Alzheimer's Disease. Each disease tends to have its own protein that goes haywire.

In the case of Parkinsons, it is the alpha-synuclein and DHA, the fish type of unsaturated fat, causes the synuclein protein to change to its toxic form that appears in Parkinsons Disease and saturated fats can protect against that and so very clearly in Parkinson's you can see the role of fat, inclining the brain towards that degenerative change in the protein and since pretty much everyone in the environment accumulates these highly unsaturated fats, especially in their brain, but in all tissues with aging, by the time you are 30 or 40, you become more and more susceptible to all of the degenerative, inflammatory diseases, very much in proportion to the unsaturated fats and you can find the breakdown products corresponding to the seriousness of Alzheimer's Disease or Huntingdon's or Multiple Sclerosis.

The specific breakdown products such as acrolein which comes largely from the omega-3 fats, the various reactive break-down products show that these unstable fats are breaking down at an increased rate in the degenerative brain conditions.

Interviewer: I see, and also in that cascade of bad effects from low blood sugar, after the free fatty acids are released, you said that it actually pulls down your whole thyroid system, maybe you could talk about that.

Dr Peat: Um yes, a series of studies in France about 30 years ago, 25-30, showed that exactly in proportion to the number of double bonds in the fat, increasing from a purely saturated fat such as stearic acid or palmitic acid through oleic acid, up increasing with linoleic, even more with linolenic and greatly with the 5 and 6 double bonds, each increased double bond impairs the thyroid function at the level of secretion, transport and response. They looked at 4 different system, different kinds of response in the cell, but every one of these was impaired in proportion to the degree of unsaturation of the pre-fatty acids in the blood.

Interviewer: When was that study done, Ray?

Dr Peat: In the 80s. In Annals of Endocrinology, in a French journal.

Interviewer: Well, they are traditionally the, and up into recent history, the 'Kings of Saturated Fat' in their cooking, French cuisine is known for its use of butter.

Dr Peat: Well the French have fallen for the propoganda against saturated fats and cholesterol and so on, to the extent that some of their famous fat researchers were convinced that giving a fish oil supplement to pregnant women would make their babies smarter, even though animal studies show that in proportion to the unsaturation of the fat in the pregnant animal's diet the babies brains were smaller and less able to learn. But anyway, the French fed some pregnant women the unsaturated fats whilst measuring
the foetus' ability to react to sounds applied to the abdomen, and they found that, contrary to what they believed would happen, the learning was impaired by the diet with more of the highly unsaturated fats and when the babies were born in line with the animal experiments, their growth was retarded.
 

pboy

Member
Joined
Jan 22, 2013
Messages
1,681
Re: Transcript project 2: AUTOIMMUNE AND MOVEMENT DISORDERS

initial section 9 verify:

There was a survey in ???palm??? at very high

"Nepal"

Your blood is more in the ???carpatino??? state

"Carbonyl"

And if you were able ???to eat chicken???,

"And if you boil a chicken"

sugar added to his ???public???foods.

"other foods"

Rest was correct!

( sorry loess, I wanted to listen so I just edited it even tho wasn't my 'task')
 

kiran

Member
Joined
Aug 9, 2012
Messages
1,054
Re: Transcript project 2: AUTOIMMUNE AND MOVEMENT DISORDERS

I'll take Part 10. But apparently I can't. It appears that I can't access either link.
 

loess

Member
Joined
Sep 22, 2013
Messages
390
Re: Transcript project 2: AUTOIMMUNE AND MOVEMENT DISORDERS

pboy, no worries man! We'll go with your edits and verification
 

dd99

Member
Joined
Apr 26, 2014
Messages
434
Re: Transcript project 2: AUTOIMMUNE AND MOVEMENT DISORDERS

Thanks for verifying part 9, pboy. Weird how happy it makes me to find get the answers to the words I couldn't understand!
 

dd99

Member
Joined
Apr 26, 2014
Messages
434
Re: Transcript project 2: AUTOIMMUNE AND MOVEMENT DISORDERS

{deleted}
 

arinryan

Member
Joined
Mar 1, 2014
Messages
47
Re: Transcript project 2: AUTOIMMUNE AND MOVEMENT DISORDERS

Parts 3 and 4 transcribed:
http://1drv.ms/1soU8fr

Sorry about transcribing two adjacent parts--I won't do it again, promise!

I would be happy to proofread parts 5 and 6.
ADDED--
Part 5 verified: http://1drv.ms/1xdNIGK
I corrected a few words, marked those with !!! surrounding, and edited a bit of the punctuation as well.
 
OP
burtlancast

burtlancast

Member
Joined
Jan 1, 2013
Messages
3,263
Re: Transcript project 2: AUTOIMMUNE AND MOVEMENT DISORDERS

kiran said:
I'll take Part 10. But apparently I can't. It appears that I can't access either link.

Part 10 goes from 53.17 to 56.22, and you can download the entire unedited interview on this forum at download/file.php?id=241
Thanks.
 

Sheila

Member
Joined
Nov 6, 2014
Messages
374
Re: Transcript project 2: AUTOIMMUNE AND MOVEMENT DISORDERS

Pls let me know what is left to verify here and i will do it this weekend.
away for a week after that, sorry.
 
OP
burtlancast

burtlancast

Member
Joined
Jan 1, 2013
Messages
3,263
Re: Project 2 (FULL): AUTOIMMUNE AND MOVEMENT DISORDERS

As far as the verifying goes:

Part 1: for ttramone
Part 2: for ttramone checks part 3
Part 3: for arinryan
Part 4: for arinryan checks part 5
Part 5: for Sheila
Part 6: for Sheila checks part 7
Part 7: for Loess
Part 8: for Loess checks part 9
Part 9: for dd99 checks part 10
Part 10: for Kiran checks part 1

I will myself check the remaining parts ( 2, 4, 6 and 8) and post here the links.

.......................................................................................................

- Part 4 checked: https://mega.co.nz/#!tZxzDCTB!Cs8uk6C_r ... TEzQAJcA4I
( very good transcript: i could only get one of the 2 inaudible words)

- Part 6 checked: https://mega.co.nz/#!scJ02RwD!t4-H5PHED ... tZS2qSW6w8
( good accurate transcript; i've sorted out the inaudible parts ( please make sure to place !!! on both parts of the inaudible word), but there's a ton of missing punctuations i had to add.)

- Part 8 checked: https://mega.co.nz/#!sQJFzLjR!pI2pOeW2h ... k9fL-PHlAs
( outstanding transcription: corrected 2 medical terms and added two more guests comments)

Thanks for your contributions, all .
:hattip
 

Similar threads

Back
Top Bottom