Lucy wrote:I've been wondering about Peat's suggestion to supplement with tiny doses of T3. I tried it and don't feel anything positive from doing it, if anything I feel worse than before (but that could be due to some other factor, not sure). When I used T3 a few years ago I had to increase to 100 mcg daily and take a large dose at once to get a resolution of my symptoms. That was also making me hyper at times, like after a sauna, so I didn't continue taking it for a long time.
Has anyone here had success with T3 supplementation? If yes, how much do you take and how often?
I nibble T3 throughout the day (including shortly after awakening and at bedtime), typically consuming around 100 mcg in total, sometimes a bit more during winter. I usually take roughly one nibble per hour; the first and last nibbles of the day are a bit larger than the others. My resting pulse is usually in the 80-90 bpm range, with occasional slight dips below 80 bpm. My hands are usually warm; my feet, less so. I'm a bit more energetic with the T3 than without.
I would describe my T3 regimen as more or less successful, but caveats are in order. In general, I would advise people to be extremely cautious with T3 and increase doses slowly (no more than a few mcg every 2-3 weeks). I'm a big, heavy guy, and my regimen will not be appropriate for everyone. To anyone considering using T3, I'd recommend reading Ray Peat's reservations about T3 in Danny R's collection of emails from Peat (http://www.dannyroddy.com/main/2011/12/ ... tandi.html
). (Search Danny's collection for the word T3.) Peat notes that T3 made his heart stop periodically, and that he felt less resilient in the face of stress without some T4.
I found a T3 regimen that worked for me, and simply have been too lazy to experiment with replacing some T3 with T4. I do think, though, that Peat makes a compelling case for using some T4 rather than T3 alone, to the extent you can handle T4. At some point, I'll be making this substitution.