lactic acid

  1. F

    Magnesium; Best form for recovery, sleep, fatigue, and soreness??

    What is the best form of Magnesium to take for people who cannot stay asleep? I have tried several different forms with no effect. I am also suffering from a lot of muscle soreness & fatigue after minimal activity. …Currently trying magnesium buffered bis glycinate with L taurine. I have...
  2. cs3000

    CoQ10 (Ubiquinone) reduces exercise induced lactate increase

    Effects of oral coenzyme Q10 on preventing the accumulation of lactic acid developing during the exercise performances of endurance skiing athletes CoQ10 levels are often reduced in people who do a lot of exercise, people who take statins. 300mg+ may interfere with exercise adaptation. but...
  3. P

    Doxycycline , intestinal health, hypertension

    Changes in Gut Microbiota Induced by Doxycycline Influence in Vascular Function and Development of Hypertension in DOCA-Salt Rats DOX decreased lactate-producing bacterial population and plasma lactate levels, improved gut barrier integrity, normalized endotoxemia, plasma noradrenaline levels...
  4. JCastro

    Fructose augments synthesis and release of free fatty acids and lactate

    Metabolic fate of fructose in human adipocytes: a targeted 13C tracer fate association study ”This study demonstrated that fructose stimulates anabolic processes in adipocytes robustly, including glutamate and de novo fatty acid synthesis. Furthermore, fructose also augments the release of free...
  5. A

    D-lactate and L-lactate - Clinical Significance of the Difference

    https://acutecaretesting.org/en/articles/l-lactate-and-d-lactate-clinical-significance-of-the-difference Modern blood gas analyzers often have incorporated sensor technology that allows measurement of plasma lactate concentration. In nature lactate exists in two isoforms: L-lactate and...
  6. haidut

    Lactate is a key driver of diabetes/obesity, by promoting inflammation

    A great study, demonstrating that in diabetes (just as in cancer) the so-called Warburg Effect (aerobic glycolysis) is as much a cause of those degenerative conditions as it is an effect of. The study below demonstrated that increased intracellular lactate results in robust increase in systemic...
  7. A

    Acute Administration of Exogenous Lactate Increases Carbohydrate Metabolism during Exercise in Mice

    In this study, we investigated the effects of exogenous lactate administration before exercise on energy substrate utilization during exercise. Mice were divided into exercise control (EX) and exercise with lactate intake (EXLA) groups; saline/lactate was administered 30 min before exercise...
  8. A

    The potential use of lactate blockers for the prevention of COVID-19 worst outcome, insights from exercise immunology

    Following the decline in Physical Activity (PA) due to COVID-19 restrictions in the form of government mandated lockdowns and closures of public spaces, the modulatory effect of physical exercise on immunity is being heavily revisited. In an attempt to comprehend the wide discrepancy in patient...
  9. Nazar

    Hyperventilation from contaminated allergic sugar or sugar?

    If I use as much as 25 or more grams of white sugar with a cup of coffee and a glass of milk among other foods - it visibly suppresses my breathing resulting in brain fog. I suspect it might be because of allergic impurities in the sugar, which is absolutely possible in my case, but I don't have...
  10. Soren

    Thyroid (t3) causes body odor change what is the cause? Should I stop?

    Has anyone ever noticed a change in body odor once they have started supplementing thyroid? My body odour has definitely gotten worse since I started which is a shame because before it was never very foul smelling now it smells quite sour and acidic. I've been supplementing with T3 during the...
  11. Mr Joe

    Asked RP about Muscles. Answer : swimming, bicycling, and tennis ?

    I've had the the opportunity to ask Ray about more details concerning building muscle and getting lean on a Ray Peat diet. The first part of the answer was like "i never go to gym" style. But i was surprised by the second part. I've asked him what his thoughts on exercice such as Dips...
  12. S

    Post Workout Lactic Acid

    I’ve started working out and I love it, getting decent muscle growth. However, I get pretty bad lactic acid build up. I experience air hunger and insomnia. I am on thyroid and feel like I am pretty peaty in supporting my metabolism. I take B-vitamins, acetic acid which I feel like should help...
  13. haidut

    Reduced pyruvate and/or increased lactate drive heart failure

    I just did a post on the role of reduced glucose metabolism, lower pyruvate/NAM/NAD and elevated lactate in the pathogenesis of glaucoma. Just minutes later, another study popped up in my newsfeed. Namely, a study that demonstrates the exact same metabolic disturbances as the main drivers of...
  14. lvysaur

    Study: Sourdough Consumption Produces Worse Symptoms

    Pilot Study: Comparison of Sourdough Wheat Bread and Yeast-Fermented Wheat Bread in Individuals with Wheat Sensitivity and Irritable Bowel Syndrome Found this interesting. Theoretically sourdough should have less gluten and fructan problems, and the study even analyzed the FODMAP content and...
  15. haidut

    Lactate Is An Oncometabolite (promotes Cancer), No Genes/mutations Needed

    It has now been more than 5 years since a seminal post/discussion on Reddit raised the question publicly of whether the dominant medical theory on cancer may actually be nothing but an elaborate fraud. Namely, a study that spurred the Reddit discussion demonstrated that that the so-called...
  16. haidut

    (Brain) Cancer Is A Metabolic Disease, Can Be Treated By Glutamine Restriction

    It seems that mainstream medicine is finally wisening up to the massacre they have been orchestrating for the last 100 years. Without much fanfare or apologies, medicine is now quietly changing its story on cancer, hoping the public won't notice as long as a cure is finally found. The study...
  17. haidut

    Baking Soda May Treat Cancer, Metformin May Cause It

    As many readers know, using baking soda to treat cancer has been labelled as "quack medicine" by many official mouthpieces of mainstream medicine, as well as by several "watchdog" groups. Here are some links "debunking" the usage of baking soda for cancer...
  18. haidut

    The Warburg "effect" Is, In Fact, A Direct Cause Of Cancer

    This is yet another recent study showing that medicine may finally be getting on the right track. Similar to the human study with doxycycline and breast cancer I just posted, confirms again what has been known and fraudulently suppressed for almost a century. Namely, the Warburg "effect" is as...
  19. haidut

    Probiotics Are Dangerous, Should Be Regulated As Drugs

    As many forum users know, Peat has spoken against the use of probiotics and in some of his articles has even linked lactic acid producing bacteria to auto-immune conditions like such as Lupus, RA, and even MS. While recently he has been recommending a bacteriophage product from LEF, he is still...
  20. haidut

    Estrogen As The Main Cause Of Cancer And Its Progression

    I think many of the forum users here know about the infamous study that generated a lot of controversy on "scientific" forums like Reddit. It basically showed that the Warburg Effect (overproduction of lactate) is not just an effect but a direct cause of cancer. So, as the top rated comment on...
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