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Dear Carnivore Dieters, A Muscle Meat Only Diet is Extremely Healing Because it is a Low "vitamin A" Diet. This is Why it Works so Well...
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obesity
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Obesity linked to mitochondrial dysfunction in GI tract, treatable by fat restriction
I think the claim that obesity can be caused by lower metabolism is not something contentious, even though mainstream medicine will claim that it only happens in clinical hypothyroidism. The so-called idiopathic obesity in the general population (now affecting 40%+ of people) is claimed to be...- haidut
- Thread
- chylomicrons diabetes enterocytes fat gi lipids mitochondria obesity
- Replies: 6
- Forum: Scientific Studies
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Optimal vitamin D intake may be at least 2,000 IU daily
As most people supplementing with vitamins know, the daily RDA for vitamin D has been set at 400 IU (in some countries up to 800 IU) daily, despite no evidence that such doses do anything beneficial, including even the basic target - preventing rickets. More recent studies have argues that the...- haidut
- Thread
- cholecalciferol diabetes dosage hypercalceimia inflammation obesity risk vitamin d
- Replies: 40
- Forum: Scientific Studies
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Obesity is estrogen-driven; Chronic fasting burns mostly muscle, not fat
I wanted to do a quick post on this, as this topic is one of the most discussed in both medicine and society in general. Namely, whether fasting is a good and healthy approach to weight loss, which is largely determined by whether the weight we lose during fasting is mostly fat or muscle. Even...- haidut
- Thread
- caloric restriction estrogen fasting fat muscle obesity stress
- Replies: 80
- Forum: Scientific Studies
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LipOdd - Liquid Product With Odd-Chain Saturated Fats (SFA)
More than a decade ago, when I was just beginning my exploration of bioenergetics, one of the first indications that Ray's writings were onto something when it came to SFA vs. PUFA was the fact that while mainstream medicine ruthlessly bashed SFA in general and promoted PUFA, virtually very... -
Cortisol stimulates its own synthesis (peripherally), drives obesity/diabetes/CVD
Synthetic/bioidentical glucocorticoids (GC) are perhaps the most widely used steroids clinically. In addition, the HPA axis, culminating in cortisol production, is one of the most widely studied mechanisms in regards to many chronic diseases including obesity, diabetes, CVD, mental conditions...- haidut
- Thread
- atheroma atherosclerosis cortisol cvd diabetes feedback hypertension obesity
- Replies: 2
- Forum: Scientific Studies
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Higher doses of vitamin D, other steroids, may be needed in obese people
The title, at least in regards to vitamin D, is something Ray commented quite a few times when people asked him what the optimal dose for raising vitamin D levels was. His response always cautioned that there is no one-size-fits-all due to the fact that in obese people vitamin D can accumulate...- haidut
- Thread
- adipose cholecalciferol obesity sequestration steroid visceral vitamin d vitamin d3
- Replies: 1
- Forum: Scientific Studies
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Inhibiting dopamine breakdown reverses obesity WITHOUT caloric restriction
Yet another study showing that the dogma we have been fed for decades - eat less and move more - is little more than a fraudulent lie. Recent studies have already demonstrated that chronic caloric restriction changes body composition for the worse - i.e. despite the weight loss, most of that...- haidut
- Thread
- 5-ht deprenyl dopamine mao-b obesity selegiline serotonin thermogenesis uncoupling
- Replies: 120
- Forum: Scientific Studies
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Androgens, glucocorticoids are antagonistic - former inhibit, latter promote fat gain
As most of my readers know, androgenic steroids are considered extremely dangerous by medicine and are in fact outlawed in most "developed" countries. Aside from the (in)famous "roid rage", medicine claims that a large number of chronic conditions (spanning the spectrum from cosmetic to...- haidut
- Thread
- androgen antagonism cortisol diabetes fat glucocorticoid obesity visceral
- Replies: 0
- Forum: Scientific Studies
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Serotonin (5-HT) drives diabetes and liver disease, blocking it is therapeutic
After more than a decade of doing research in bioenergetics, I have come to the conclusion that there is hardly a disease (both acute and chronic) where 5-HT is not involved as a causal factor. Out of all those conditions, the ones with the biggest public health impacts are probably obesity...- haidut
- Thread
- 5-ht diabetes fibrosis inflammation nafld nash obesity serotonin
- Replies: 5
- Forum: Scientific Studies
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P
Obesity/insulin resistant and impared glycine synthesis
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9219591/ Hypoglycinemia in participants with morbid obesity was associated with impaired de novo glycine synthesis. The increase in plasma glycine concentration and de novo glycine synthesis plus the marked improvement in insulin resistance after...- paymanz
- Thread
- glycine insulin resistance insulin sensitivity obesity
- Replies: 0
- Forum: Scientific Studies
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Aspirin reduces risk of developing diabetes
Not sure if my readers have noticed it, but Big Pharma has drastically increased their bashing of aspirin since the pandemic started. Those attacks began when a few studies published back in 2020 demonstrated that aspirin users had a much lower risk of both contracting and dying from COVID-19...- haidut
- Thread
- aspirin diabetes fatty acid oxidation inflammation lipolysis obesity
- Replies: 12
- Forum: Scientific Studies
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Chronic stress doubles the weight gain from high-fat diets
I am only posting this to demonstrate that the (in)famous claim so many doctors and dietitians and public health figures like to quote (calories in = calories out) does not hold and in fact body weight is heavily influenced by environmental conditions as well, such as chronic stress. As the...- haidut
- Thread
- brain cortisol diabetes glutamate obesity satiety stress
- Replies: 7
- Forum: Scientific Studies
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Media: Endotoxin (LPS) drives obesity/diabetes
I did not think we will ever see such a headline in a major news outlet, but here is is. And in The Guardian of all places, which is a newspaper that rarely deviates from the official medical narrative on any condition, especially obesity and diabetes. The official narrative for those conditions...- haidut
- Thread
- diabetes endotoxin inflammation lps obesity oxphos pufa
- Replies: 9
- Forum: Scientific Studies
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Regaining weight post diet/exercise due to lowered metabolism by increased PUFA in cardiolipin
This is by far the most significant study I have seen come out in the last 2-3 years, simply because of the impact it has on virtually every person out there who has tried to lose excess weight (and who hasn't?). Virtually every person considering (or having done) dieting/exercise to lose excess...- haidut
- Thread
- cardiolipin diet exercise fasting obesity oxphos pufa
- Replies: 117
- Forum: Scientific Studies
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Century-long metabolic decline, not less exercise and/or more eating, causing the obesity epidemic
I did a few posts years ago on the alarming findings that the youngest generations are among the most physically active, consume the least amount of calories, yet are the most obese (on average) compared to previous generations going back to at least the 1950s. Those studies did not look at...- haidut
- Thread
- bmr diabetes diet exercise obesity pufa
- Replies: 52
- Forum: Scientific Studies
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Blocking estrogen (and/or taking DHEA) prevents menopausal obesity, diabetes, osteoporosis, etc
A remarkable study, which for a reasonable person should unilaterally invalidate the mainstream dogma that menopause is a condition of estrogen "deficiency", and that most of the symptoms associated with menopause (of which osteoporosis, infertility, obesity and insulin resistance are among the...- haidut
- Thread
- dhea diabetes estrogen insulin menopause obesity osteoporosis
- Replies: 10
- Forum: Scientific Studies
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PUFA metabolite (prostaglandin) promotes lipolysis / fibrosis, causes obesity / diabetes
Just in case there are still doubts out there about just how detrimental PUFA is to our health, here is a study showing that just one of PUFA's "normal" metabolites (i.e. enzymatically derived, instead of through peroxidation) is sufficient to elevate lipolysis, and that effect alone is enough...- haidut
- Thread
- aspirin cox diabetes fibrosis lipolysis obesity pge2 prostaglandin pufa
- Replies: 2
- Forum: Scientific Studies
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Can anyone help me find this study that Ray references?
Ray talks about a group of women trying to lose weight who were found to be able to gain weight on even 700 calories a day, where the food was controlled in metabolic wards. He mentions it here, for example: View: https://youtu.be/yylOTFJFxko?t=1203 Does anyone know what study he's referring...- EnergeticLeo
- Thread
- obesity thyroid weight gain
- Replies: 0
- Forum: Metabolism
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Low-dose niacinamide has striking anti-obesity effects
It looks like the medical world has firmly set its sights on the bioenergetic wave/target, as the number of scientific papers focusing on niacinamide, NAD/NADH ratio and OXPHOS in general has been steadily climbing since 2010. That would be good news, despite the attempts of companies such as...- haidut
- Thread
- co2 nad nampt niacinamide nicotinamide obesity oxphos vitamin b3
- Replies: 189
- Forum: Scientific Studies
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Fructose augments synthesis and release of free fatty acids and lactate
Metabolic fate of fructose in human adipocytes: a targeted 13C tracer fate association study ”This study demonstrated that fructose stimulates anabolic processes in adipocytes robustly, including glutamate and de novo fatty acid synthesis. Furthermore, fructose also augments the release of free...