progesterone

  1. Mauritio

    Cyanidin-3-O-glucoside (C3G), the next polyphenolic StAR ?

    Through reading about polyphenols I discovered this interesting compound that possibly has some interesting effects. It seems to boost Progesterone,Pregnenolone and Testosterone and various steroidogenic enzymes, especially the rate limiting enzyme StAR (hence the title). It also increases the...
  2. NatachaRose

    Female cat sterilization or natural progesterone?

    What would be the worst-case scenario between sterilization and supplementing with Progest E to prevent heat cycles for my female cat? Additionally, do you have any idea how much Progest E I should give her to prevent the onset of heat?
  3. J

    OMG PROGESTERONE IS SEDATING ME....

    I need some help. ] I've been applying Progesterone many times a day and live by the alarm clock. Problem is I'm at 1600mg for heavy bleeding and thought that I'd switch my vaginal prometrium to sublingual. I am doing 200mg ona's vaginally 5 times a day and Progest-E 5 drops 5 times a day...
  4. J

    Explain permanent gains from Progesterone

    Can someone explain how one achieves permanent gains from progesterone? Is it even possible? I have read accounts where people stop progesterone and their levels go back to before. Is it possible for progesterone to heal a body enough where it runs efficiently on its own, progesterone is no...
  5. J

    Topical prometrium?

    Anyone try Prometrium topically? Would it be as effective as Progest-E topically?
  6. J

    Why would progesterone make fibroids worse?

    I'm on a facebook progesterone page and there is a member there who says progesterone made her bleed more and fibroids worse over time. Why would this be the case?? I thought progesterone is suppose to help not worsen. She said using estrogen settled everything. Is there something we are...
  7. D

    Can you get increasingly nauseous from using Progest-E over several months?

    My GF has taken progest E for about 3-4 months. Starting from about a month ago, she has started to become nauseous from taking it. If she takes her daily 3x3 drops too close to each other, or she takes it without having eaten anything in the morning. This didnt happen before. 2 days ago she got...
  8. J

    Severely dry skin from Vitex/Calcium D glucarate

    Ok in a desperate attempt to lower my prolactin and estrogen, I ended up with dry skin and hair. I notice with Vitex it caused either dopamine or adrenaline surges at high dose. Along with the Calcium D glucarate I noticed my hair was starting to sound like straw when I tried to tie it up. My...
  9. J

    Lowering prolactin is tough

    Is it meant to be this uncomfortable to lower prolactin? I’m taking a fairly high dose of Vitex 2000mg to lower my high prolactin and raise progesterone. Trying to stop some female bleeding. Its been causing agitation, buzzing/static in head and ears, light sensitivity, vision disturbances and...
  10. J

    Vitex Prolactin

    https://www.cjmb.org/uploads/pdf/pdf_CJMB_465.pdf I’m trying to understand how Vitex is able to lower prolactin, yet raise estradiol according to this pdf. Is this why Vitex is dose dependent? It states it’s beneficial effects dropped off by 5th cycle. Does this mean Vitex loses effect if...
  11. L

    Does Katherine/Kenogen still sell Progest-E? How much vitamin e is in Progest-E?

    Does Katherine/Kenogen as a company still sell Progest-E directly to costumers? My thread in 2021: https://raypeatforum.com/community/threads/which-website-to-buy-progest-e-from.42104/ Does anyone know how much vitamin E is in Progest-E?
  12. learnedhelpless

    Progesterone therapy in men (transgender women), does not significantly effect, testosterone, libido and weight

    This is a 2 month old study, so it is not available on Sci Hub, but given that the doses of progesterone, for gender - reassignment, are 100–400 mg/day, this shows that when progesterone is used in super-physoligical doses that are 50x / 2250 % - 200x /19900% greater than the average production...
  13. F

    RPF approved/peaty "PCT" protocol for testosterone base cycle?

    I've decided I want to run testosterone base indefinitely for muscle building and libido purposes, but want to be careful that I have a way to recover my natural hormone production after cycle. I've run a steroid cycle before a few years back, and hoped to use SERMs to recover, as is...
  14. J

    Calcium D Glucarate+Prunella Vulgaris for someone 69+?

    Can my mother, who is 69 years old take Calcium D Glucarate? I understand that this is to remove excess estrogens and her blood test levels are <40 pmol/L. I'm unsure if these are lower levels as the ranges on the results page are for those who still have a menstrual cycle. Can she take CDG...
  15. Soren

    Late stage brain cancer any advice?

    Hi all. A friend of mine has late stage brain cancer. He has been very reluctant up to this point to try any alternative therapies and is on a very large dose of morphine constantly for the pain. The last thing he has been on is some form of genome therapy but has been told that it won´t do...
  16. haidut

    Parkinson Disease (PD) is metabolic, of gut origin, progesterone to the rescue

    One of the most famous sayings in medicine since antiquity has been Hippocrates' quip that "all disease begins in the gut". Despite millennia that passed since that phrase was first uttered and countless "advances" in our knowledge of diseases, evidence continues to accumulate that the ancients...
  17. PopSocket

    Puffy nipples due to progesterone (male) Breast enlargement Need advice how to quickly reverse.

    I am on Topical Testosterone (60-90mg per day). Never before had issues with T therapy even when not controlling E, have done many cycles using different methods. Never nipple or breast issue due to high E. Decided I am going to add Progesterone as it has always been low for me and on T it gets...
  18. X

    Hormonal blood test - Need your help please

    Hi everyone, (30M) here, I've just done a blood test. Unfortunately, it would take me months to see a doctor here in Canada and even then, I wouldn't put too much faith in their reading. Should I be concerned about my progesterone which is out of range? I have an autoimmune disease but my...
  19. Mauritio

    Progesterone babies are more intelligent

    I was looking for this study for a long time. I found it here: -https://twitter.com/BradCohn/status/1688615871797743617 In this paper they looked at the efefct that progesterone had on the offpspring. To make it short: progesterone babies are intellectually superior. The effect was dose...
  20. Charger

    Guidance for 36-year-old female, labs included.

    Below are labs for my sister who is in her mid-30s. I am trying to assist her with optimizing her health/hormones. I'm less versed on what the optimal levels for women are and would be interested in advice from other women and the usual reputable posters (@haidut, @Hans, etc.) as far as possible...
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