reverse tolerance

  1. NewACC

    Study on acute and chronic effects of serotonin (5HT) antagonists on serotonin binding sites

    https://doi.org/10.1007/bf00497017 "The administration of 14 daily doses of cyproheptadine, BC-105, metergoline and methysergide induced a marked decrease in the number (B max) of 3H-spiroperidol binding sites (5HT2 sites) in frontal cortex, when assayed 48 h after the last dose; the apparent...
  2. A

    Microdosing to reverse tolerance

    I found this very interesting thread that claim microdosing stimulants like amphetamine can long-term sensitize dopamine receptors View: https://www.reddit.com/r/Stims/comments/3mbp3n/be_very_careful_with_low_doses_of_stimulants/ ”In rats, dopaminergic supersensitivity from low-dosage...
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