Interesting to note, however, that periodontal cells do not exhibit endotoxin tolerance:
Human periodontal ligament cells exhibit no endotoxin tolerance upon stimulation with Porphyromonas gingivalis lipopolysaccharide.
So I could very well be endotoxin-tolerant systemically, but not locally in my periodontal tissues where the infection is located. As a matter of fact, I do get occasional flare-ups in the form of inflamed gingival granulomas, as mentioned previously (which I can swiftly put to an end with SSKI), but don't remember ever getting these so-called high endotoxin state symptoms, as discussed in this thread.
Human periodontal ligament cells exhibit no endotoxin tolerance upon stimulation with Porphyromonas gingivalis lipopolysaccharide.
So I could very well be endotoxin-tolerant systemically, but not locally in my periodontal tissues where the infection is located. As a matter of fact, I do get occasional flare-ups in the form of inflamed gingival granulomas, as mentioned previously (which I can swiftly put to an end with SSKI), but don't remember ever getting these so-called high endotoxin state symptoms, as discussed in this thread.
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