aguilaroja
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Antidepressant-Induced Serotonin Syndrome a Danger for the Elderly
Researchers found that 25% of elderly patients taking antidepressants had serotonin syndrome, which is potentially life-threatening.
www.madinamerica.com
"...researchers found that 25% of elderly patients taking antidepressants had serotonin syndrome, which is potentially life-threatening. In addition, women and patients on multiple antidepressant drugs or a higher dose were at increased risk"
"Of the 238 participants, 60 (25.2%) had serotonin syndrome. In 31.7% of the patients, the serotonin syndrome was considered mild, while in 68.3%, it was classed as moderate. (Although mild serotonin syndrome is unlikely to be fatal, it is still debilitating and will likely persist unless the serotonergic drug is discontinued.)
Women were twice as likely as men to have serotonin syndrome. Those taking at least two antidepressants were also at twice the risk of serotonin syndrome. Those taking an SSRI and an SNRI were 18 times more likely to have serotonin syndrome."
Antidepressant-induced serotonin syndrome in older patients: a cross-sectional study - PubMed
The widespread single or combined use of antidepressants in older adults represents an increased clinical concern for SS and physicians should be aware of this drug-related complication in older patients.
pubmed.ncbi.nlm.nih.gov
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