dht

  1. haidut

    DHEA Is Preferentially Converted Into DHT In Humans

    I posted several studies showing both that DHEA itself is androgenic and very similar to DHT in terms of affecting "gene" expressions, as well as preferentially converted into DHT when used as supplement. Unfortunately, most of the studies were in animals and some of them were in vitro. So, what...
  2. N

    Finasteride Activity Against Candida Albicans

    For those of you who don't believe in DHT as a cause for hairloss, this might be an alternative mechanism that could explain Finasteride's effectiveness. Note that 80% of population is infested with candida in the oral cavity and/or the GI tract, which is normally kept in check by the immune...
  3. haidut

    Why DHEA Must Be Taken In Small Doses Only

    Once again, I am amazed at how well Ray's recommendations are backed by science. He has said that taking DHEA is fine and can restore proper youthful hormone balance. However, he cautioned that DHEA should only be taken in doses of no more than 10mg at once and preferably no more than 15mg...
  4. E

    DHT Production Depends On Stress

    http://www.ncbi.nlm.nih.gov/pubmed/19615370 "5alpha-R isozymes (5alpha-R1 and 5alpha-R2) mRNA and protein levels were detected in prefrontal cortex of male and female rats after they underwent environmental stresses, i.e., excessive heat, artificial light, and the sensation of immobility in a...
  5. haidut

    Oral Progesterone Increases Testosterone And DHT

    This rodent study shows that a hefty oral dose of progesterone stimulated synthesis of and elevated the levels of both testosterone and DHT. It seems that if progesterone has any negative effects on male steroids it requires dosages higher than the ones used in the study. Speaking of dosages...
  6. haidut

    Vitamin A Increases DHT By Enhancing 5-alpha Reductase

    Rat study, and it used preformed all-trans-retinoic acid (ATRA) but it should hold true for retinol and its various esters like retinyl acetate/palmitate. The human dosage for ATRA was in the range 500mg-700mg, which is a huge dose. http://www.ncbi.nlm.nih.gov/pubmed/10423178...
  7. haidut

    DHEA Has Very Similar Anabolic Activity To DHT

    As a follow up to the studies I posted on DHEA increasing DHT in animals and thus improving metabolic parameters, this study compared the effects of DHEA and DHT on several human tissues and found them to be quite similar. Consequently, in lower doses DHEA may indeed convert mostly into...
  8. haidut

    DHEA Provides Same Benefits Effects As Exercise By Increasing DHT

    This is a follow up study to the one I posted earlier. This study by the same authors wanted to assess whether exercise was superior to DHEA administration in improving insulin resistance and blood glucose in obese rats. The results were that DHEA and exercise exert the same benefits and both...
  9. haidut

    Low dose DHEA restores insulin sensitivity by increasing DHT

    This is one study that used doses of DHEA close to what Peat would recommend, and not the megadosing schedules likely to result in conversion into estrogen. The human equivalent dose was <15mg per day and resulted in 71% increases in DHT. It is that increase in DHT and DHEA levels that is behind...
  10. haidut

    Pregnenolone, Progesterone And Androsterone Are Aromatase Inhibitors

    I have seen some people in the forum claim that they thought pregnenolone increased their estrogen levels. According to this study, pregnenolone should in fact lower estrogen by inhibiting aromatase. Peat has already written extensively on progesterone being a known aromatase inhibitor, so that...
    • haidut
    • Thread
    • androsterone aromatase aromatase inhibition dht inhibitor pregnenolone progesterone
    • Replies: 125
    • Forum: Scientific Studies
  11. haidut

    Caffeine Increases DHT By Enhancing 5-alpha Reductase

    I know many people who have taken drugs like Finasteride for hair loss and prostate enlargement (BPH). The mechanism of action of those drugs is inhibition of the enzyme 5-alpha reductase (5-AR) and thus lowering levels of DHT, since DHT is blamed for the hair and prostate issues. Actually, DHT...
  12. haidut

    Chronic Caffeine Ingestion Increases T And DHT Levels

    There have been several threads on this forum about raising testosterone (T) levels in males, and especially dihydrotestosterone (DHT) levels. DHT is considered the "king" of male hormones since it does not aromatize into estrogen (E), has very strong anabolic (i.e. building muscle and reducing...
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