Follow along with the video below to see how to install our site as a web app on your home screen.
Note: This feature may not be available in some browsers.
Click Here if you want to upgrade your account
If you were able to post but cannot do so now, send an email to admin at raypeatforum dot com and include your username and we will fix that right up for you.
I noticed that as well experimenting with choline and antihistamines. What brand of phosphatidylcholine do you use?I mentioned this recently in a thread but thought I would make a separate post about it.
Cyproheptadine and other antihistamines like benadryl, because of their strong anticholinergic properties, will increase fatty liver in those predisposed to low Choline levels.
I myself have a genetic predisposition for very low Choline, meaning the anticholinergics peat often recommends are a terrible idea because Choline is essential for estrogen detoxification and reduction of fatty liver.
For years I was using cyproheptadine without understanding it was making my fatty liver and overall estrogenicity much much worse.
I've just started supplementing phosphatidylcholine and at last my belly is getting flat, manboobs reducing a lot, etc.
For those with a well functioning PEMT enzyme and good choline levels I can absolutely see the benefits of cyproheptadine, but anyone with possible fatty liver issues and low Choline, I would strongly recommend to avoid.
I find this interesting because when I started using cypro I barely had any cortisol left in my body & my adrenals we're limping along.Cyproheptadine blocks cortisol so if the person is under stress and is hypothyroid and operating on adrenaline and cortisol and using fat as energy and burning fat then starts taking cyproheptadine which stops this stress induced fat burning, this could lead to weight gain.
This is the same reason why everyone going from low calorie, low carb diet to Peat diet having all these new things which lower stress hormones and stop the stress induced fat burning and muscle wasting, they start putting on weight which is a sign of health.
I think the best person to ask about this is @Terma he talks about cyproheptadine and choline.
We can speculate the the increased hunger is from the lowering of stress hormones.I find this interesting because when I started using cypro I barely had any cortisol left in my body & my adrenals we're limping along.
So the concept that the weight gain is from lowering high cortisol doesn't apply to me. In fact I was actually concerned about what it would do considering my cortisol levels were already dangerously low.
Yet, I packed on 8+ pounds in two months from Cypro after a year of slowly & evenly gaining from pro-metabolic eating.
It did make me hungrier for the first few weeks but after that my hunger cues returned to normal.
All the places I've gained on in the last few months are for sure indictive of a rise in estrogen, which I was low in.
Anyhow just thought I'd share.
If my stress hormones drop any lower I'd be in an adrenaline crisis.We can speculate the the increased hunger is from the lowering of stress hormones.
The way I under stand it, is that the adrenal hormones are there for acute stressful emergency situations but primarily a healthy persons thyroid gland will working and the HPA axis in the background.If my stress hormones drop any lower I'd be in an adrenaline crisis.
Possibly serotonin, yeah I know that's a stress hormone. But it's for sure not from lowering my cortisol/adrenaline because they're already on the floor.
Cyproheptadine blocks cortisol so if the person is under stress and is hypothyroid and operating on adrenaline and cortisol and using fat as energy and burning fat then starts taking cyproheptadine which stops this stress induced fat burning, this could lead to weight gain.
This is the same reason why everyone going from low calorie, low carb diet to Peat diet having all these new things which lower stress hormones and stop the stress induced fat burning and muscle wasting, they start putting on weight which is a sign of health.
I think the best person to ask about this is @Terma he talks about cyproheptadine and choline.
The two things with stomach fat are it’s been found that it can be due to elevated cortisol and that it’s visceral fat than it’s not good but if it’s subcutaneous then I’m not sure.A lot of people here put that weight on the belly though. Which, apart from not looking healthy, is pretty much observed from most (if not all) health circles as being one of the worst places to put it. I think with a Peat approach you have to be very wary of the randle cycle. Either high carb/low fat or high fat/low carb seem to work for a person in terms of keeping weight healthy and not packing weight onto the belly area. Gorging on saturated fats combined with consuming unlimited amounts of fructose seems to be a dodgy combination for me anyway.
Do you have mutations in the PEMT gene? I have a lot. I think I couldI mentioned this recently in a thread but thought I would make a separate post about it.
Cyproheptadine and other antihistamines like benadryl, because of their strong anticholinergic properties, will increase fatty liver in those predisposed to low Choline levels.
I myself have a genetic predisposition for very low Choline, meaning the anticholinergics peat often recommends are a terrible idea because Choline is essential for estrogen detoxification and reduction of fatty liver.
For years I was using cyproheptadine without understanding it was making my fatty liver and overall estrogenicity much much worse.
I've just started supplementing phosphatidylcholine and at last my belly is getting flat, manboobs reducing a lot, etc.
For those with a well functioning PEMT enzyme and good choline levels I can absolutely see the benefits of cyproheptadine, but anyone with possible fatty liver issues and low Choline, I would strongly recommend to avoid.
Nvm I now see you already talked about it above !Do you have mutations in the PEMT gene? I have a lot. I think I could
Benefit from supplementing phos -choline for my liver /gallbladder. And maybe use Tudca and taurine too .. how do you know for certain you have Choline deficiency ?
Hey Tommy yes all of my PEMT genes are ****88. Homozygous. Be careful you don't want to take too much choline but people like us really do need topping every now and againDo you have mutations in the PEMT gene? I have a lot. I think I could
Benefit from supplementing phos -choline for my liver /gallbladder. And maybe use Tudca and taurine too .. how do you know for certain you have Choline deficiency ?
What do you think of my screenshot? Could benefit from choline supps ? I also checked the other genes someone wrote above related to PEMF and I have a lot of homo for themHey Tommy yes all of my PEMT genes are ****88. Homozygous. Be careful you don't want to take too much choline but people like us really do need topping every now and again
Interesting I'll have to log back in to have a look.So I just used self decode 4 years later. What’s funny is they have about 18 variants now for PEMT. And the percentage changed very much. And only the 4s7946 is still there. So the other 2 in your picture above they got rid of. But added many other ones
I actually have a good amount of genes for low serotonin . So idk how I feelInteresting I'll have to log back in to have a look.
This post is pretty old but reading it back I want to clarify as much as I put on significant weight gain when I started cyproheptadine (I also started T3 and progesterone around the same time) I gained many many things in terms of better mental health, stopped my male pattern baldness, amazing sleep, possible anti aging properties, happier in myself, significant lowering in stress.
I still use cyproheptadine but I also occasionally need some choline.
If you do supplement choline try if possible saturated forms - eggs, beef, mitolipin etc.
Not to sidetrack the thread but you just threw me down the rabbit hole of Self decode.So I just used self decode 4 years later. What’s funny is they have about 18 variants now for PEMT. And the percentage changed very much. And only the 4s7946 is still there. So the other 2 in your picture above they got rid of. But added many other ones
It’s the PEMT geneNot to sidetrack the thread but you just threw me down the rabbit hole of Self decode.
I'm uploading my DNA to their services now and I'm curious where you found this particular section at?
Thanks!It’s the PEMT gene