Westside PUFAs
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- Feb 4, 2015
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"The Randle cycle, also known as the glucose fatty-acid cycle, is a metabolic process involving the competition of glucose and fatty acids for substrates. It is theorized to play a role in explaining type 2 diabetes and insulin resistance." - Wikipedia
Roddy:
"Some basic things that I think are missing from the above is the role of pyruvate decarboxylation, which generates more carbon dioxide from the breakdown of glucose that fats; the role of prostaglandins in health and disease (i.e., high fat diets are typically higher in polyunsaturated fats); the role of hepatic glycogen in the resistance to metabolic stress (i.e., the conversion of glucose to lactic acid and the increased functioning of adrenaline, cortisol, estrogen, growth hormone, etc.); and the role of the so-called "Randle cycle" that exists even in the presence of an excess of saturated fats."
from the comment section of: https://www.youtube.com/watch?v=OHL7CyKoHPE
It's not just PUFA that's involved in the Randle Cycle, saturated fat as well.
Roddy:
"Some basic things that I think are missing from the above is the role of pyruvate decarboxylation, which generates more carbon dioxide from the breakdown of glucose that fats; the role of prostaglandins in health and disease (i.e., high fat diets are typically higher in polyunsaturated fats); the role of hepatic glycogen in the resistance to metabolic stress (i.e., the conversion of glucose to lactic acid and the increased functioning of adrenaline, cortisol, estrogen, growth hormone, etc.); and the role of the so-called "Randle cycle" that exists even in the presence of an excess of saturated fats."
from the comment section of: https://www.youtube.com/watch?v=OHL7CyKoHPE
It's not just PUFA that's involved in the Randle Cycle, saturated fat as well.