mostlylurking
Member
I did many years of low-carb dieting. I also was raised on PUFA and did not get it out of my diet until 2015 (at age 65) when I found Ray Peat's website.Thank you @TheSir.
@mostlylurking, thanks for the info. I have tried quite a few things; among those discussed on this forum frequently has been high-dose aspirin, high-dose niacinamide + taurine, and a few of the different forms of thiamine + supporting B vitamins as well. None of them have really made a dent. Prior to that, I went for years low-carb + strenuous exercise to keep BG "under control". That probably damaged my glucose metabolism even more in the long-run, especially given my ancestry and the problems they've had with the issue.
I'm now moving toward the RP style of eating as it just makes too much sense, and am trying to avoid going low-carb again in order to control BG w/o drugs.
I believe that besides PUFA poisoning I may be missing some X-Factor(s) that have been depleted thru years of the SAD diet + years of low-carb. I have not given mineral supplementation a fair shot, and haven't tried Manganese at all, so am looking for an effective manganese supplement to take along with a "multi-mineral" type supplement.
Are you taking any biotin? I've found biotin to be very helpful. Here's some info on biotin:
Protective effect of supplementation with biotin against high-fructose-induced metabolic syndrome in rats - PubMed
Several reports have demonstrated that pharmacological concentrations of biotin reduce hyperglycemia, hypertriglyceridemia, and hypertension. We hypothesized that biotin could exert a protective effect on some illness-associated metabolic syndrome. To test this hypothesis, male Wistar rats were...
pubmed.ncbi.nlm.nih.gov
Chromium picolinate and biotin combination improves glucose metabolism in treated, uncontrolled overweight to obese patients with type 2 diabetes - PubMed
These results suggest that the chromium picolinate/biotin combination, administered as an adjuvant to current prescription anti-diabetic medication, can improve glycaemic control in overweight to obese individuals with type 2 diabetes; especially those patients with poor glycaemic control on...
pubmed.ncbi.nlm.nih.gov
Biotin supplementation improves glucose and insulin tolerances in genetically diabetic KK mice - PubMed
Because biotin treatment may lower blood glucose in insulin-dependent diabetes, we chose to study such an effect in non-insulin dependent diabetes. Twenty-six diabetic KK mice, moderately hyperglycemic and insulin resistant, were treated for 10 weeks: 9 animals with 2 mg of biotin/Kg, 8 with 4...
pubmed.ncbi.nlm.nih.gov
[Effects of biotin on blood glucose regulation in type 2 diabetes rat model] - PubMed
The possible mechanism of the decreasing biotin blood sugar in diabetic rats may by promoting the synthesis of glycogenand reducing gluconeogenesis.
pubmed.ncbi.nlm.nih.gov
I take a tiny little pinch of biotin each morning (about 1/64th (?) of a teaspoon). I have not experimented with taking more; this small amount seems to be helpful for me.
I'm taking high dose thiamine hcl; 1 gram 2Xday. It lowers my blood sugar to the point that I'm really hungry within an hour of taking it. I know that 2 grams/day sounds like a lot but thiamine hcl does not absorb very well in the small intestine. 2 grams/day for 7 days is said to equal a single 100mg injection of thiamine hcl per week (see Dr. Costantini's information here).