From: Cholesterol, longevity, intelligence, and health.
So in an ideal situation, LDL is low because it is constantly turned into pregnenolone through the action of thyroid and using vitamin A. But when LDL is high and there are a lot of free radicals (for example, because of a high PUFA burden), than high LDL can cause the formation of cholesterol deposits in arteries, which increase the risk of CVD.
Do I understand this correctly? @haidut
I'm asking this because my girlfriend wants me to inform her father about cholesterol (who has high BP and athersclerosis).
I'm afraid that if I explain him the benefits about cholesterol.
He may stop his cholesterol lowering medication.
But if he then for example continues eating french fries, fried in sunflower oil, his risk of dying of CVD may actually become higher.
Ray Peat said:Stress accelerates the oxidation of the polyunsaturated fatty acids in the body, so people who consume unsaturated vegetable oils and fish will have some oxidized cholesterol in their tissues. The constant turnover of cholesterol in the tissues tends to lower the proportion of the toxic oxidized degradation products of cholesterol, but in hypothyroidism, the use of cholesterol is slowed, allowing the toxic forms to accumulate.
So in an ideal situation, LDL is low because it is constantly turned into pregnenolone through the action of thyroid and using vitamin A. But when LDL is high and there are a lot of free radicals (for example, because of a high PUFA burden), than high LDL can cause the formation of cholesterol deposits in arteries, which increase the risk of CVD.
Do I understand this correctly? @haidut
I'm asking this because my girlfriend wants me to inform her father about cholesterol (who has high BP and athersclerosis).
I'm afraid that if I explain him the benefits about cholesterol.
He may stop his cholesterol lowering medication.
But if he then for example continues eating french fries, fried in sunflower oil, his risk of dying of CVD may actually become higher.