Suikerbuik
Member
- Joined
- Jan 25, 2014
- Messages
- 700
Many times I see people mentioning estrogen, but what does estrogen really do? I hope this topic to go beyond standard "oh estrogen is involved you should lower it" if possible. I want to know what it is doing at molecular level. I know this is by far not completely understood but we are in the era that this research is being done and may provide us better insights.
What is the role of estrogen alpha-/ beta receptor? What factors (proteins), so no food components, are involved in the expression of alpha-/beta receptor and aromatase? Is it the ratio between this two that matters? What genes are affected in terms of expression (so how does it change the interactome, casuing symptoms?)? What is the inhibitory capacity of for example progestrone and other natural things that should balanced estrogen?
If there's paper's describing interesting genomic and non-genomic effects of estrogen, you can mention them in this topic.
http://www.cell.com/cell/abstract/S0092-8674(11)00376-X
What is the role of estrogen alpha-/ beta receptor? What factors (proteins), so no food components, are involved in the expression of alpha-/beta receptor and aromatase? Is it the ratio between this two that matters? What genes are affected in terms of expression (so how does it change the interactome, casuing symptoms?)? What is the inhibitory capacity of for example progestrone and other natural things that should balanced estrogen?
If there's paper's describing interesting genomic and non-genomic effects of estrogen, you can mention them in this topic.
http://www.cell.com/cell/abstract/S0092-8674(11)00376-X