Everything but the Jab!

Peatress

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Beatrix_

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I was close to putting on the heating last night - this morning the BBC was bull****** about heatwaves.

My local news is reporting 120,000 deaths in Europe from climate change 🤡
 

Peatress

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Edward Dowd has been dissecting the UK disability data.

“This is the greatest cover-up I’ve ever seen in my life.” Disability claims are on the rise, and people are wondering why. “If it’s not the SARS CoV-2 mRNA gene therapy injection (vaccine), what is it?” - Edward Dowd

Edward Dowd's Website
THEY LIED, PEOPLE DIED.
 
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Peatress

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The new figures for England show that more than 84,000 patients were admitted to hospital because of a heart attack in 2021/22 – a rise of more than 7,000 in a year.

It follows warnings that heart deaths have risen by more than 500 a week since the first lockdown, with a fall in the numbers prescribed vital medication amid struggles to access GP care.

Health officials are afraid that people are still failing to come forward, adding to the collateral damage caused by the pandemic.

From this week, an NHS advert will encourage people to call 999 as soon as they experience symptoms of a heart attack, such as squeezing across the chest, sweating and a feeling of uneasiness, so people have the best chance of survival.
 

David PS

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All the implied premises are fallacies

nature npj vaccines articles article
Article
Open Access
Published: 27 September 2023
Duration of SARS-CoV-2 mRNA vaccine persistence and factors associated with cardiac involvement in recently vaccinated patients


LNP = lipid nanoparticle

Abstract
At the start of the COVID-19 pandemic, the BNT162b2 (BioNTech-Pfizer) and mRNA-1273 (Moderna) mRNA vaccines were expediently designed and mass produced. Both vaccines produce the full-length SARS-CoV-2 spike protein for gain of immunity and have greatly reduced mortality and morbidity from SARS-CoV-2 infection. The distribution and duration of SARS-CoV-2 mRNA vaccine persistence in human tissues is unclear. Here, we developed specific RT-qPCR-based assays to detect each mRNA vaccine and screened lymph nodes, liver, spleen, and myocardium from recently vaccinated deceased patients. Vaccine was detected in the axillary lymph nodes in the majority of patients dying within 30 days of vaccination, but not in patients dying more than 30 days from vaccination. Vaccine was not detected in the mediastinal lymph nodes, spleen, or liver. Vaccine was detected in the myocardium in a subset of patients vaccinated within 30 days of death. Cardiac ventricles in which vaccine was detected had healing myocardial injury at the time of vaccination and had more myocardial macrophages than the cardiac ventricles in which vaccine was not detected. These results suggest that SARS-CoV-2 mRNA vaccines routinely persist up to 30 days from vaccination and can be detected in the heart.

Discussion
The biodistribution and duration of persistence of SARS-CoV-2 mRNA vaccines may be important for understanding some of the uncommon side-effects of these new agents15. In this autopsy study, SARS-CoV-2 mRNA vaccines were routinely detected by RT-qPCR in axillary lymph nodes within 30 days of vaccination, in agreement with a previous study analyzing axillary lymph node biopsies by in-situ hybridization18. We did not detect vaccine mRNA in mediastinal lymph nodes, consistent with the previous observation that SARS-CoV-2 mRNA vaccines elicit antigen-specific germinal center B cell responses only in draining lymph nodes24. Vaccine was not detected by RT-qPCR in the liver or spleen in any of the patients in this study. The absence of detectable vaccine in the liver or spleen was surprising since the liver and spleen had been implicated as sites of vaccine accumulation in pre-clinical rodent studies employing LNPs simulating BNT162b2 and mRNA-1273 respectively16,17. However, these pre-clinical rodent studies employed much higher doses of LNPs than are given to patients, potentially explaining the negative results in this study.

An important finding in this study, was the detection of SARS-CoV-2 vaccine mRNA in human heart tissue. Using an RT-qPCR assay, the BNT162b2 vaccine was detected in two left ventricular samples and two right ventricular samples from a total of three patients. Cardiac ventricles in which vaccine was detected had healing myocardial injury at the time of vaccination and had more myocardial macrophages than the cardiac ventricles in which vaccine was not detected. As outlined in the results section, the myocardial injury in these patients was most likely due to the patients’ underlying diseases and not a result of the vaccine itself. It is not known if phagocytic cells transported vaccine mRNA into sites of healing myocardial injury. However, it has been reported that SARS-CoV-2 mRNA vaccines circulate primarily in the plasma compartment rather than the cellular compartment19. Another possibility is that the myocardial injury was associated with microvascular permeability changes that allowed circulating vaccine to more efficiently enter the myocardium. Importantly, the liver samples in these patients did not show evidence of similar healing injury. It is also possible that the vaccine LNP’s entered the myocardium by paracellular transport or transcytosis involving intact endothelium in areas of healthy cardiac tissue.

An important adverse complication of SARS-CoV-2 mRNA vaccines is myocarditis8,9. While vaccine antigen expression by cardiac myocytes could potentially be a mechanism for myocarditis, we were unable to localize the vaccine antigen by immunohistochemistry, and only observed non-specific staining in both the vaccinated and non-vaccinated control patients. Also, the patients in this study with vaccine detected in the heart were older patients with significant medical conditions, while vaccine-associated myocarditis tends to involve younger patients. None of the patients in this study showed pathologic features of myocarditis. Thus, the relationship of SARS-CoV-2 vaccine distributing to and persisting in the heart and the development of myocarditis is unclear. However, given that SARS-CoV-2 mRNA vaccine was detected in heart muscle with healing injury and that the effects are unclear at the present time, it may be prudent to consider delaying LNP-based vaccination in patients with recent myocardial infarction.

This study has several limitations. Importantly the number of patients with vaccine detected in the heart was very small, making it not possible to definitively determine the reasons vaccine can be detected in the heart in specific patients. This study does not address the specific mechanisms by which vaccine may enter into different organs from the bloodstream. Also, the samples taken for histology and the samples taken for RT-qPCR were random samples; the areas of myocardial injury were microscopic and not visible grossly. Thus, it is not certain that the samples taken for RT-qPCR in the patients with vaccine detected in the heart also contained the myocardial injury present histologically. Only small portions of each organ were examined by RT-qPCR and anti-spike immunohistochemistry, and it is not certain that the tissues sampled are completely representative of the entire organs in terms of the presence of vaccine. Finally, the possibility that variations in post-mortem mRNA degradation between different organs affected the biodistribution of the vaccine observed here cannot be excluded.

In conclusion, this study provides a map of the biodistribution and persistence of SARS-CoV-2 mRNA vaccines in human tissues. A complete understanding of this biodistribution and time course of persistence will be essential as LNP-based vaccines become more widely used for a multitude of pathogens.
 
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David PS

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David PS

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Beatrix_

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HEALTHWATCH
U.S. infant mortality rate rises for first time in 20 years; "definitely concerning," one researcher says

UPDATED ON: NOVEMBER 1, 2023 / 8:42 AM EDT / CBS/AP

The U.S. infant mortality rate rose 3% last year — the largest increase in two decades, according to the Centers for Disease Control and Prevention.

White and Native American infants, infant boys and babies born at 37 weeks or earlier had significant death rate increases. The CDC's report, published Wednesday, also noted larger increases for two of the leading causes of infant deaths — maternal complications and bacterial meningitis.

"It's definitely concerning, given that it's going in the opposite direction from what it has been," said Marie Thoma, a University of Maryland researcher who studies maternal and infant mortality.

Dr. Eric Eichenwald, a Philadelphia-based neonatologist, called the new data "disturbing," but said experts at this point can only speculate as to why a statistic that generally has been falling for decades rose sharply in 2022.

RSV and flu infections rebounded last fall after two years of pandemic precautions, filling pediatric emergency rooms across the country. "That could potentially account for some of it," said Eichenwald, who chairs an American Academy of Pediatrics committee that writes guidelines for medical care of newborns.

Infant mortality is the measure of how many babies die before they reach their first birthday. Because the number of babies born in the U.S. varies from year to year, researchers instead calculate rates to better compare infant mortality over time. The U.S. infant mortality rate has been worse than other high-income countries, which experts have attributed to poverty, inadequate prenatal care and other possibilities. But even so, the U.S. rate generally gradually improved because of medical advances and public health efforts.

The national rate rose to 5.6 infant deaths per 1,000 live births in 2022, up from from 5.44 per 1,000 the year before, the new report said.

The increase may seem small, but it's the first statistically significant jump in the rate since the increase between 2001 and 2002, said Danielle Ely, the CDC report's lead author. She also said researchers couldn't establish whether the 2022 rise was a one-year statistical blip - or the beginning of a more lasting trend.

The CDC said preliminary data suggests the increase is continuing, with quarterly rates in the first quarter of 2023 higher than they were at the same time in 2022.

Overall in the U.S., the death rate fell 5% in 2022 — a general decrease that's been attributed to the waning impact of the COVID-19 pandemic, especially on people 65 and older. U.S. maternal deaths also fell last year.

More than 30 states saw at least slight rises in infant mortality rates in 2022, but four had statistically significant increases - Georgia, Iowa, Missouri and Texas.

In numbers, U.S. infant deaths surpassed 20,500 in 2022 — 610 more than the year before nationwide. Georgia had 116 more infant deaths than the year before, and Texas had 251 more.

"It would appear that some of the states could be having a larger impact on the (national) rate," Ely said, adding that smaller increases elsewhere also have an effect - and that it's hard to parse out exactly what places, policies or other factors are behind the national statistic.
 
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