~The ubquitous use of glyphosate can almost guarantee contamination in the US, even on organic pastures. My guess is that the contamination is reduced with well sourced animal foods and home made broths. Considering the conflict with sourcing products from Brazil (forest clearing, regulation of products etc...) I cant be certain what the figures for contamination are or the reliabilty of the info.
~Here are some resources where the glycine/ glyphosate claims have been made and theorized in depth;
"FIGURE 1: Four examples of amino acids. Glycine, the simplest amino acid, has no side chains. Alanine is the second simplest amino acid, which has a simple side chain consisting of a methyl group (CH3). Glyphosate is a glycine molecule with the side chain on the nitrogen atom instead of the traditional form with a side chain on the carbon atom. Proline is a unique amino acid with the side chain circling around so that it becomes attached to both the central carbon and the nitrogen molecule. The circles indicate the core structure of the molecule, which defines its membership in the “amino acid” class of molecules. Note that both glyphosate and proline have lost one hydrogen bound to the nitrogen atom, but this does not prevent them from linking up in the amino acid chain that makes up a peptide in a protein."
FIGURE 2: Schematic of how glyphosate substitution for glycine in a protein can totally disturb the shape of the pocket where the substrate for the enzymatic action would normally fit snugly.
https://www.westonaprice.org/health-topics/environmental-toxins/glyphosate-in-collagen/
Beecham J, Seneff S. The possible link between autism and glyphosate acting as glycine mimetic – a review of evidence from the literature with analysis. J Mol Genet Med 2015; 9:4.
~This excerpt and theory from Jack Kruse is also interesting but presented in the usual *personal hypothesis* Jack Kruse fashion. Parts of it make sense/ are established while the rest is based off of newer research hypothesis on Deuterium;
"Anything that can affect endogenous glutathione creation from methionine can clear heavy metals and glyphosate. Methionine, selenium, serine, and glycine all are capable of doing this. All work better when done the in the sun. I used this survivor soup hack to clear myself of glyphosate from my California wines. It works because of the serine-glycine interconversion pathway (3PG) helps augment more light hydrogen into TCA/urea cycle intermediates (while lowering methionine) and removes some of the deuterium in the cycle to improve their kinetics. The glycine cleavage system, refuels one-carbon metabolism; a complex cyclic metabolic network based on chemical reactions of folate compounds. This is where methionine comes in. It is an essential amino acid that when controlled can improve longevity or when it gets too high in cells and plasma can kill you and raise your calcium index score via its action of homocysteine (HC). Normally we can recycle HC to regain our methionine so we do not have to eat it. Folate is also loaded with hydrogen (3 of them) that must be deuterium depleted to work in methylation pathways for dopamine, glutathione, and DNA/RNA. It turns out methionine controls the flow of hydrogen on histones to methylated them. So......glycine and serine in broths have mechanisms similar to drinking DDW. Neither works as well, but it is an awesome hack to know about. "
~ and no, I dont know of any tested ones but I have been liking (and trusting) PaleoPro, which I believe is US sourced (without the natural flavors) but its not gelatin. I used to also use Vital Proteins plain Gelatin but the whole "Brazil cow hide sourcing" thing turned me off. However, I usually make my own broth from local, pasture raised ox tail and joints.
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