[Interrelationship between manganese, vitamin B1 and the level of pyruvic acid]. - PubMed - NCBI
Abstract
Addition of manganese to the diets promotes an increase of the total thiamine content in the blood and the liver, heart and brain tissues. This trace element appreciably changes the correlation between different thiamine fractions. The free vitamin B1 level in the blood and tissues decreases, while the level of its bound form (pyrophosphatic) increases. All the administered manganese doses induced a statistically significant reduction of pyruvic acid concentration in the blood.
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Manganese and Vitamin B1
Manganese and Vitamin B 1
BEFORE the annual meeting of the American Society of Experimental
Physiology held in Toronto, 1939, was presented a report on Manganese
and Vitamin B 1-. Experiments with animals have recently shown that an
excess of vitamin B 1 may develop disturbances in lactation and maternal
instinct associated with cannibalism. This phenomena was found to be
due to a depletion of the manganese supply. It is' found that vitamin B 1
and manganese are synergistic and an excess of vitamin B 1 uses up the
manganese supply. On the other hand an excess of manganese brings about
the exhaustion of vitamin B 1. Because of this when vitamin B 1 is rein-forced in the diet or is given in the form of thiamin chloride care must be
taken to insure a sufficient supply of manganese.
Abstract
Addition of manganese to the diets promotes an increase of the total thiamine content in the blood and the liver, heart and brain tissues. This trace element appreciably changes the correlation between different thiamine fractions. The free vitamin B1 level in the blood and tissues decreases, while the level of its bound form (pyrophosphatic) increases. All the administered manganese doses induced a statistically significant reduction of pyruvic acid concentration in the blood.
-----------------------
Manganese and Vitamin B1
Manganese and Vitamin B 1
BEFORE the annual meeting of the American Society of Experimental
Physiology held in Toronto, 1939, was presented a report on Manganese
and Vitamin B 1-. Experiments with animals have recently shown that an
excess of vitamin B 1 may develop disturbances in lactation and maternal
instinct associated with cannibalism. This phenomena was found to be
due to a depletion of the manganese supply. It is' found that vitamin B 1
and manganese are synergistic and an excess of vitamin B 1 uses up the
manganese supply. On the other hand an excess of manganese brings about
the exhaustion of vitamin B 1. Because of this when vitamin B 1 is rein-forced in the diet or is given in the form of thiamin chloride care must be
taken to insure a sufficient supply of manganese.
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