Xavage
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- Jan 3, 2021
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Mortality risk of vaccination is 7 times higher than that of COVID-19 in 20s
Introduction:
Disproportionate increase of death from cardiovascular diseases was observed both among medical workers and elderly people who received COVID-19 vaccine compared with general population [1].
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Adverse Reactions
However, the mortality rate beyond 28 days should be lower than that within 28 days, so the mortality risk ratio after vaccination in 20s may be between 5 to 40 times higher compared with death from COVID-19 (sex adjusted risk ratio may be between 7 and 52).
The estimated number of vaccinations inoculated for people in their 20s by July 23 is somewhat inaccurate because vaccination to people other than medical workers aged under 65 years started in June, but older people were recommended to be vaccinated earlier than younger people. Therefore, the age distribution of people vaccinated is totally unknown. If people aged under 65 years had COVID-19 vaccine proportionally as general population, number of vaccination in people in their 20s is estimated to be 3 million doses (about 2 million persons).
By July 30, 1 week later, 7 people had died after vaccination (Note 1). By using these data, mortality risk ratio of vaccinated people to COVID-19 mortality risk does not change significantly. Harm of vaccination in children may be enormous
There were no deaths due to COVID-19 infection under the age of 20 until September 1, 2021. If children in this age group are vaccinated, it may cause death. Mortality risk from vaccination may be lower in children than people in their 20s. Even so, the mortality risk ratio cannot be calculated because the number of death from COVID-19 is "0" in Japan until September 1, 2021(Note 2).
The clinical trial of AstraZeneca's vaccine for children aged 6 to 17 years old was interrupted [8]. It was due to 79 cases of thrombosis with thrombocytopenia of which 19 have died were reported in adults, as the UK Medicines and Healthcare products Regulatory Agency (MHRA) announced on April 7, 2021 [9].
A c c o r d i n g t o a r e p o r t o n t h e o u t b r e a k i n Massachusetts, more vaccinated people were diagnosed with COVID-19 than non-vaccinated people, most of which were delta strain infected: odds ratio= 1.26,p=0.025[10,11]. Hospitalization rate was 1% in the outbreak in Massachusetts. No death was reported among 469 confirmed COVID-19 patients. Hence, the mortality risk from delta strain COVID-19 is not high. It is far lower than the case mortality rate (almost 6%) in May 2020 in the United States. Although delta strain is very infectious, it does not seem to be very toxic at least in the U.S. where 1 out of 9 people have already had confirmed COVID-19 overall case fatality rate is 1.68 % on August 19 [12], and most people have been infected at least once with SARSCoV-2
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The Ministry of Health, Labour and Welfare (MHLW) announced on October 22, 2021 that they received a total of 1308 reports of death after inoculation of COVID-19 vaccine by October 15, (1268 and 44 reports after Pfizer's and Moderna's, respectively) [1]. These death cases include 3 teens (all males) for whom brief case reports are available [1].
In addition, the approximate numbers of vaccinated people by age (every 10 years) until October 8 are available [2]. By using these data, causality between the deaths of the 3 teens and vaccination is discussed.
Case 1: Pfizer vaccine, death case number 1167 [3] A 16-year-old male received the 1st inoculation on August 10, 2021. He had no underlying illness. On the 6th day after vaccination, he suddenly arrested. His spontaneous circulation was resumed from ventricular fibrillation after treatment by DC defibrillator. He was intubated and mechanically ventilated but died on September 1, 2021 (22nd day of vaccination).
Cause of death:
Reported: Non-obstructive intestinal ischemia Corresponding MedDRA PT: Intestinal ischemia Evidence basis for determining the cause: CT, blood test, electrocardiogram Causality assessment: Reported: cannot be assessed
Experts: γ (cannot be assessed) with the following comments: A 16-year-old male who suddenly arrested 6 days after the first vaccination and died. It is difficult to evaluate the cause with the current information. Comments by MedCheck:
"Intestinal ischemia" that caused sudden cardiac arrest may be due to a blood clot in the fairly large mesenteric artery causing its obstruction. A healthy 16-year-old boy with no underlying disorder suffered from thrombosis of the intestinal (perhaps mesenteric) artery on the 6th day of vaccination, suffered from cardiac arrest and died 22 days after vaccination. It would be extremely rare for this to happen by chance.
In the vital statistics 2019, among those between the ages of 10 and 14, 2 males died of myocardial infarction, but death from cerebral infarction and other arterial embolisms or thrombosis was 0 among those between the ages of 10 and 19.
Therefore, it is almost certain that this boy died probably from intestinal thrombosis which was caused by the vaccine.
Case 2: Pfizer vaccine, death case number 961 [3] A 16-year-old male received the 1st inoculation on July 15, 2021, died on July 23, 2021. Underlying disorder: attention deficit hyperactivity disorder. The psychiatrist had previously prescribed medication, but recently he had stopped taking it by himself and self-harm was observed. Cause of death: Reported: Suicide (falling from the top floor of the condominium)
Corresponding MedDRA PT: Suicide attempted
Evidence basis for determining the cause: Unknown Causality assessment:
Reported: Not related (Possibility of other causes: Yes, attention deficit hyperactivity disorder)
Specialists: γ (cannot be assessed) without comments
Comments by MedCheck:
There is another case of "suicide" after COVID-19 vaccination. A 25-year-old male had a fever after receiving the COVID-19 vaccine (Pfizer), which might have resulted in transient "febrile delirium". However, he was diagnosed with a psychosis and was recommended of consultation by psychiatrist. While he was being transported to a psychiatric hospital by car, he jumped out of the car and died accidentally. Then, the doctor determined the cause of death as "suicide" [4].
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