haidut said:narouz said:haidut said:Such_Saturation said:If the brain half life is thirty hours, shouldn't you have like a pound of it by now?
I'd second this. Higher doses of MB are only meant to be used for short periods of time. It will build up in the brain and it starts becoming toxic at 5uM. The depression study in humans used 15mg for 2 weeks.
I stopped my high dose experiment after 1 week and now I take high doses only as needed and space it out by several days.
Most people should aim for 1mg-2mg daily as that is the amount producing the optimal concentrations in cells.
haidut-
What do you make of the study
showing max effectiveness for dementia
at 60mg x 3/day dosage.
As I recall the subjects took that dose for a long time...many months.
In the interview called "Nitric Acid" (I think) w/ The Herb Doctors
Peat personally seemed persuaded of MB's safety,
even when taken at very high levels over a long period of time.
Can't remember exactly what the high levels were now,
but they registered with me at the time as ridiculously high....
*edit: just replied to haidut's earlier post without noting these intervening similar posts.....
Then I would like to see that statement from Peat b/c from the things I have heard from him it sounds like he thinks the OPTIMAL dose would be <=1mg per day. Why the studies used more than that I am not sure about. Maybe a higher dose would get quicker response in serious diseases like AD.
Yeah...
I've been taking it at doses similar to you for a while.
But I'm giving it to my dad (dementia) at about 30-60mg x 3/day.
So...I've got a dual focus here.
I just listened to that "Nitric Oxide" interview today,
so I'll try to see over the weekend if I can get you Peat's words.
I have read (your?) reports about Peat saying mcg doses probably being most effective for most.
But...in the interview, at least, he came across as very okay with the high dose/safety aspect.
And he tends to be cautious/conservative....