Makrosky
Member
- Joined
- Oct 5, 2014
- Messages
- 3,982
I am using minocycline right now at 100mg x day and made some pubmed searches on its safety. I am shocked guys!!
Mino and the other cyclines like doxy and tetra can cause intracranial hypertension, one of its effects could be permanent vision loss.
The more dangerous of the three is minocycline because of its lipophilic properties.
I have emailed Ray to see what he thinks about all this.
I think considering the massive ammount of people using then, it would be very rare to develop it but still... something to consider. Read the new zealand link posted below, it is very informative and concise.
Guys sorry but I am too lazy to post all abstracts, I'm on my smartphone (can't access a computer) and it's a pain in the **** to do so. Just click on this link and see the studies yourselves :
Minocycline intracranial - PubMed - NCBI
Doxycycline and Headaches: What everyone needs to know.
https://medsafe.govt.nz/profs/puarticles/bih.htm
WHO Drug Information Vol. 17, No. 1, 2003: Safety Issues: Minocycline and intracranial hypertension
@haidut
From other medical sources :
Mino and the other cyclines like doxy and tetra can cause intracranial hypertension, one of its effects could be permanent vision loss.
The more dangerous of the three is minocycline because of its lipophilic properties.
I have emailed Ray to see what he thinks about all this.
I think considering the massive ammount of people using then, it would be very rare to develop it but still... something to consider. Read the new zealand link posted below, it is very informative and concise.
Guys sorry but I am too lazy to post all abstracts, I'm on my smartphone (can't access a computer) and it's a pain in the **** to do so. Just click on this link and see the studies yourselves :
Minocycline intracranial - PubMed - NCBI
Doxycycline and Headaches: What everyone needs to know.
https://medsafe.govt.nz/profs/puarticles/bih.htm
WHO Drug Information Vol. 17, No. 1, 2003: Safety Issues: Minocycline and intracranial hypertension
@haidut
From other medical sources :
DO NOT PRESCRIBE WITH ISOTRETINOIN Isotretinoin and tetracyclines are both associated with benign intracranial hypertension (BIH), so the combination of tetracyclines with oral vitamin A or retinoids is contraindicated.1,2 BIH is a very rare but potentially serious condition and minocycline is the most frequently reported medicine associated with BIH in the literature (approximately 9% of all cases).9 The presenting complaint is usually a pulsatile headache; visual disturbance and pulsatile tinnitus have also been reported. Symptoms generally occur within the first 4 weeks of treatment.9 Actively ask about headaches and visual disturbance at each visit. If BIH is suspected, discontinue treatment immediately4 and seek neurological advice.9 The condition may completely resolve, but a delay in diagnosis can lead to lasting visual defects, and even blindness.9 Dizziness, light-headedness, vertigo and reduced hearing have also been associated with tetracyclines, especially minocycline. Advise caution with driving if these symptoms occur.1
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