kineticz
Member
Hi all been a while since my methylation thread got locked.
I found out that I have hemochromatosis, but it gets worse, I not only retain iron, I had low stomach acid so I wasn't absorbing iron either! With my family history of kidney disease you can understand my life's struggle. A sluggish liver and anemia cause high phosphates which leach calcium in the bone.
I wanted to say that you CAN become iron deficient if you are vitamin B2 deficient. This becomes low under high phoshorus and high oxidative stress/low glutathione redox.
So calcium IS needed to strengthen bone but the issue is while it might lower PTH, phosphate clearance and still be poor and this is driven by anemia and low stomach acid. Low stomach acid causes high lactic acid and this further demineralises bone to buffer the pH.
The reason magnesium helps therefore in high amounts is because it decalcifies your mitochondria which lowers lactic acid and serum phosphates. You then increase your calcium intake to rebuild your bone marrow.
The methylation posts continue to aid my health, I would give one word of warning which I give in my methylation, be very careful with methyl b12 as they are quick to push it on Freddd's forum but methyl b12 if you are malnourished is very bad, it lowers potassium, ceruloplasmin, b2, b6 - I have felt first hand the congestive heart problems with low potassium, and later I found out that low B2 causes low stomach acid so you become iron deficient! B12 is also very taxxing on your lipid membranes so it can alter your brain chemistry if you are low on oils and fats.
Malnutrition, edema and anemia are NOT pleasant so proceed carefully. A tank in liver function with heavy handedness of B12 causes high serum phosphates and brittle bones which is heavily damaging to the kidneys and further promotes anemia since bone marrow is where blood is made.
So Ray is right to urge against overmethylating with B12 and to use niacinamide. Potassium produces the necessary carbon dioxide to demethylate and then you take calcium to improve red cell production.
All the best
Dan
UK
I found out that I have hemochromatosis, but it gets worse, I not only retain iron, I had low stomach acid so I wasn't absorbing iron either! With my family history of kidney disease you can understand my life's struggle. A sluggish liver and anemia cause high phosphates which leach calcium in the bone.
I wanted to say that you CAN become iron deficient if you are vitamin B2 deficient. This becomes low under high phoshorus and high oxidative stress/low glutathione redox.
So calcium IS needed to strengthen bone but the issue is while it might lower PTH, phosphate clearance and still be poor and this is driven by anemia and low stomach acid. Low stomach acid causes high lactic acid and this further demineralises bone to buffer the pH.
The reason magnesium helps therefore in high amounts is because it decalcifies your mitochondria which lowers lactic acid and serum phosphates. You then increase your calcium intake to rebuild your bone marrow.
The methylation posts continue to aid my health, I would give one word of warning which I give in my methylation, be very careful with methyl b12 as they are quick to push it on Freddd's forum but methyl b12 if you are malnourished is very bad, it lowers potassium, ceruloplasmin, b2, b6 - I have felt first hand the congestive heart problems with low potassium, and later I found out that low B2 causes low stomach acid so you become iron deficient! B12 is also very taxxing on your lipid membranes so it can alter your brain chemistry if you are low on oils and fats.
Malnutrition, edema and anemia are NOT pleasant so proceed carefully. A tank in liver function with heavy handedness of B12 causes high serum phosphates and brittle bones which is heavily damaging to the kidneys and further promotes anemia since bone marrow is where blood is made.
So Ray is right to urge against overmethylating with B12 and to use niacinamide. Potassium produces the necessary carbon dioxide to demethylate and then you take calcium to improve red cell production.
All the best
Dan
UK