Andrew Kims latest blog is relevant to this thread:
http://www.andrewkimblog.com/2012/12/po ... g-and.html
http://www.andrewkimblog.com/2012/12/po ... g-and.html
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Yes, big key!!narouz said:Here is that cool bit supplied by nwo2012 I mentioned above:
nwo2012 said:I asked Ray a while back about this. His answer says all I needed to know.
RP
Thyroid and sugar help the liver to detoxify them by glucuronidation, without having to oxidize them.
Thanks, Charlie. It has me talking to the screen.Charlie said:Andrew Kims latest blog is relevant to this thread:
http://www.andrewkimblog.com/2012/12/po ... g-and.html
The ingestion of glucose or starch induces oxidative stress in humans, producing optimal conditions for PUFA peroxidation (ultimately into the same α-oxoaldehydes as glucose). Fruit and fructose, however, do not and affords protection from starch or glucose induced stresses to some degree.
Birdie said:I figure to do it all for 2 years. Then you'd be down to half of your starting pufa. I was off grains for many years and stopped seed oils years ago, but I continued DHA in big doses.jyb said:Birdie said:From Rob at functionalps:
“The larger the quantity of “toxic fat” stored in the body, the more careful the person must be about increasing metabolic and physical activity. Using more vitamin E, short-chain saturated fats, and other anti-lipid-peroxidation agents is important.” Ray Peat
So, RP says it takes 4 years when is storage is high. But what about thin people? I'm hypo yet have always been slim, no matter how much and how bad I eat.
But I have a chronic condition that I want to improve. Makes me motivated. Fortunately, I've been on NDT for 15+ years, but still... I'm on the slim side too, but that is not no matter how much I eat.
Haha, Charlie... Yes, definitely in a good way. And I did some catching up on Andrew's other articles. :)Charlie said:Hopefully talking in a good way? I have only got a chance to scan it over quickly but have not had the chance to get into it yet. My brain needs a break.
Fruit and fructose for the win!
I think that in 2 years, which is 1 year away for me, I will be at the 50% mark with pufa detox. If you get to 100% at 4 years a la Peat, then, I figure that by year 2 you'll be at 50%.jyb said:Birdie said:I figure to do it all for 2 years. Then you'd be down to half of your starting pufa. I was off grains for many years and stopped seed oils years ago, but I continued DHA in big doses.jyb said:Birdie said:From Rob at functionalps:
“The larger the quantity of “toxic fat” stored in the body, the more careful the person must be about increasing metabolic and physical activity. Using more vitamin E, short-chain saturated fats, and other anti-lipid-peroxidation agents is important.” Ray Peat
So, RP says it takes 4 years when is storage is high. But what about thin people? I'm hypo yet have always been slim, no matter how much and how bad I eat.
But I have a chronic condition that I want to improve. Makes me motivated. Fortunately, I've been on NDT for 15+ years, but still... I'm on the slim side too, but that is not no matter how much I eat.
So you think that even though you are thin, some PUFA are stored and it will take 2 years...is that a guess or you have evidence?
I'll look forward to talking to my screen on this one. We're all so interested... Thanks, Andrew.Andrew Kim said:Birdie, the rate at which PUFA are released from adipose tissue is now on my queue of blog posts to write. Thanks.
Andrew Kim said:Birdie, the rate at which PUFA are released from adipose tissue is now on my queue of blog posts to write. Thanks.
narouz said:I think I've heard speak about PUFA storage in the body in terms of "half-life."
Being very stupid about science, I have only a dim understanding of what that means.
I've heard it applied to radioactive isotopes,
but that would seem like a different kind of measurement...?
In any case, Peat, I think, has said that the half-life of PUFA stored in our bodies is about 2 years.
So, I think that means that the full-life would be four years
(I don't know why the half-life thing is worth bothering with ).
4 years for most of the oil stored in your body to turn over is what I've heard,
without the fancypants scientific half-life terminology.
And Peat has said that is variable, person-to-person,
based upon how much fat you have stored,
how much of that fat is PUFA,
and how efficiently your metabolism is running
(and thereby removing PUFA through chelation by way of the liver).
Charlie said:4 years just turned into 10+ years.
j. said:Charlie said:4 years just turned into 10+ years.
I don't think so. The half life I think is 400 days, not 2 years. I'm fairly confident narouz just guessed that 2 years number.
Ray Peat said:The half-life of fats in human adipose tissue is about 600 days, meaning that significant amounts of previously consumed oils will still be present up to four years after they have been removed from the diet. [4] According to Draper, et al., [5]