Nothing really surprising, as far as Peatarians are concerned, in the findings of this study. I am only posting it here as it is one of the few that officially acknowledge that serotonergic drugs cause sexual dysfunction - i.e. something mainstream medicine has vehemently denied for decades. As such, it corroborates the approach of using anti-serotonin drugs such as cyproheptadine or low-dose (25mg-50mg daily) Benadryl, as well as dopamine agonists of the ergot class for the treatment of so-called PSSD - the persistent sexual dysfunction induced by serotonergic drugs. The study also explains why/how chronic stress inhibits libido - i.e. stress is known to powerfully elevate serotonin and lower dopamine. And last but not least, since these neurotransmitters play a key role in reproductive health as well, the study below demonstrates how/why stress causes infertility (in both sexes). The good news is that the therapies I mentioned above are applicable for both the lack of libido and infertility, whether caused by stress or by pharmacological poisons such as SSRI drugs.
Hypothalamic dopamine neurons motivate mating through persistent cAMP signalling - PubMed
"...The researchers propose that elevated serotonin may act as a brake on dopamine signaling in mating-related circuits, thereby decreasing libido—a side effect that nearly 75% of patients taking SSRIs experience. The scientists suggest that future therapies could target the newly identified dopamine-releasing neurons that regulate the drive to mate to alleviate the problem, thereby eliminating a major reason patients discontinue taking antidepressant medications."
Hypothalamic dopamine neurons motivate mating through persistent cAMP signalling - PubMed
Sex Drive Linked to Medication-Sensitive Neuronal Signaling Mechanism
Sexual hunger or satiety has been shown to be regulated by cAMP mechanism in dopamine-releasing cells, suggesting that new antidepressants might avoid side effects on libido.
www.genengnews.com