methylenewhite
Member
- Joined
- Aug 21, 2018
- Messages
- 1,237
Many members including me complain about side effects of carrot salad outweighing benefits. We believe it's b-carotene being absorbed. So I was thinking how to suppress b-carotene absorption. Its easier then I initially thought. Carotenoids compete to be absorbed. And lutein greatly diminishes b-carotene absorption.
Effect of simultaneous, single oral doses of beta-carotene with lutein or lycopene on the beta-carotene and retinyl ester responses in the triacylg... - PubMed - NCBI
In conclusion, this study showed that lutein, but not lycopene, negatively affected beta-carotene absorption when given simultaneously with beta-carotene but apparently had no effect on beta-carotene cleavage.
It means we still get some vitamin A created by b-carotene cleavage. Another study found that the process of competition is ratio dependent.
https://www.researchgate.net/public...f_lutein_on_-carotene_absorption_and_cleavage
In a comparative study with two beta-carotene/lutein ratios (2:1 and 1:2, respectively), this inhibitory effect of lutein was found to be most marked when lutein was the predominant carotenoid. In studies on plasma (serum) response also an inhibitory effect of beta-carotene on lutein response was observed.
https://www.agriculturejournals.cz/publicFiles/01951.pdf
The carotene content of carrots ranges from 60–120 mg/100 g, but some varietes can contain up to 300 mg/100 g (Velíšek 1999)
This amount of carotene could probably be outweighed by a sane portion of kale or spinach.
In theory it looks good. I don't know how would this suppressing dose of lutein affect overall health and thyroid function especially. I would appreciate any contribution in this investigation.
Effect of simultaneous, single oral doses of beta-carotene with lutein or lycopene on the beta-carotene and retinyl ester responses in the triacylg... - PubMed - NCBI
In conclusion, this study showed that lutein, but not lycopene, negatively affected beta-carotene absorption when given simultaneously with beta-carotene but apparently had no effect on beta-carotene cleavage.
It means we still get some vitamin A created by b-carotene cleavage. Another study found that the process of competition is ratio dependent.
https://www.researchgate.net/public...f_lutein_on_-carotene_absorption_and_cleavage
In a comparative study with two beta-carotene/lutein ratios (2:1 and 1:2, respectively), this inhibitory effect of lutein was found to be most marked when lutein was the predominant carotenoid. In studies on plasma (serum) response also an inhibitory effect of beta-carotene on lutein response was observed.
https://www.agriculturejournals.cz/publicFiles/01951.pdf
The carotene content of carrots ranges from 60–120 mg/100 g, but some varietes can contain up to 300 mg/100 g (Velíšek 1999)
This amount of carotene could probably be outweighed by a sane portion of kale or spinach.
In theory it looks good. I don't know how would this suppressing dose of lutein affect overall health and thyroid function especially. I would appreciate any contribution in this investigation.