ecstatichamster
Member
- Joined
- Nov 21, 2015
- Messages
- 10,537
So investing in b complex is what you’re implying?
I think it can help. B1 increases CO2 in the body.
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So investing in b complex is what you’re implying?
but you said above "I’ve observed people who are highly stressed out, when they start T3, can be very low in stress hormones." - suggesting that the stress hormones are somehow necessary for t3 to function properly.I don’t believe this theory about “t3 needs sufficient cortisol.”
@Jon do you also think pregnenolone stops insomnia from t3 because it's replacing a lack of cholesterol?What is happening is, cholesterol and steroidogenesis is insufficient for downstream hormone production. If your cholesterol is not good and high, that will be a stress on the body. Pregnenolone takes the place of cholesterol.
but you said above "I’ve observed people who are highly stressed out, when they start T3, can be very low in stress hormones." - suggesting that the stress hormones are somehow necessary for t3 to function properly.
@Jon do you also think pregnenolone stops insomnia from t3 because it's replacing a lack of cholesterol?
I presumed my chronically very high LDL tended to mean I wasn't short of cholesterol, but maybe that's my issue.
Have you ever run any labs to verify/observe effects of pregnenolone? How much pregnenolone was taken (and with what else)?No I don’t really think that’s what’s happening. Pregnenolone is kind of like the “blank slate” of hormones. It can be converted into basically whatever the body needs (hormonally) BUT I believe it has less of a tendency to convert to estrogens and stress hormones or interfere with androgens, unlike progesterone. I think it helps with insomnia by resupplying the adrenals with materials to synthesize more cortisol (which a lack of can often be the cause of insomnia which occurs by way of a reverse cortisol circadian rhythm) and can this help return cortisol release to a proper circadian rhythm. High LDL can be a sign you’re eating too much refined sugar.
i think you're spot on with this commentI think it helps with insomnia by resupplying the adrenals with materials to synthesize more cortisol (which a lack of can often be the cause of insomnia which occurs by way of a reverse cortisol circadian rhythm) and can this help return cortisol release to a proper circadian rhythm.
This struck me because I'm mega hypo and probably got there via raw, low sodium and used to take tons of zinc. I bet there's a connection between low sodium days and high cortisol/sleep quality nights. I need liver, and maybe copper supps?root cause is low sodium and low copper
Just received Recovering w/T3 and The Thyroid Patient's Manual. Desperate to feel human again.According to Paul Robinson who started the CT3M protocol and has helped thousands of people with thyroid disorders, the insomnia is caused by high adrenaline. He says t3 needs sufficient cortisol, and when cortisol levels are lacking, adrenaline increases and causes heart palpitations and insomnia etc. the fact that prednisone, pregnenolone and adrenal cortex all stop the insomnia and heart palpitations for me would vindicate his theory
Does zinc in the PM mess w/your sleep?Paul explains in his books the incessant palpitations are caused by high adrenaline. ive tried well known anti adrenaline peat suggestions like taurine, zinc, inosine, they all work to stop the palpitations from t3, confirming for me that it is just an adrenaline issue
Advice on dose/timing?I think Progesterone could help
Still taking that much daily Preg?I’m taking 300mg of pregnenolone a day along with T3, and 1000mg of thiamine. It seems to be helpful in reducing muscle aches and pains, finally.
Thank you. Considering progesterone or an adrenal glandular because I've stopped responding to thyroid and pregnenolone seems to be going to estrogen? Super hypo, lipids rising, belly fat/gyno., maybe glucose issues (Bs?)…Guys I think we always forget that Ray has said things about balance. I wish I could find quotes about Ray when he says that progesterone compliments estrogen. We always think of estrogen as completely bad but Ray has even said that it's essential for certain things up to a point. The same thing with cortisol it complements thyroid. You have to have good cortisol levels to have good thyroid levels, they mirror each other. Nothing is bad in our body, otherwise it wouldn't be there. It's about balance and we want more progesterone to cortisol ratio, testosterone to estrogen ratio, and progesterone estrogen ratio, . Good thyroid function makes more youthful steroids. one person I know took too much t3 and almost had a heart attack. Because they didn't listen and take pregnealone progesterone with it to make more cortisol.
Progesterone makes cortisol. when there is enough cortisol then progesterone can stack up. Ray Peat told Danny Roddy that the hormone tree is like a rope where if you need something you get more slack, but when there's enough it will even out.
Stress will use up cortisol, which ultimately uses up progesterone. So by supplementing progesterone we make more cortisol to fill up our adrenal system. Then progesterone doesn't need to go to cortisol anymore and will do the progesterone things.
Did you ever try progesterone? Thyroid stops working for me after a few days as well, and it starts causing stress response.Thank you. Considering progesterone or an adrenal glandular because I've stopped responding to thyroid and pregnenolone seems to be going to estrogen? Super hypo, lipids rising, belly fat/gyno., maybe glucose issues (Bs?)…
I recently used large topical, and some oral, doses (Progest-e/50-150 mg) for several days after a bad back/disc injury/flare. It's analgesic and helped w/pain, sleep and also bumped temp a bit. I've discontinued to normalize levels and will probably reintroduce small oral doses (3-6mg/day) with 1/3rd the amount DHEA in a couple months.Did you ever try progesterone? Thyroid stops working for me after a few days as well, and it starts causing stress response.
My stress hormones have been out of whack for years before this (frequent panic attacks, especially in the morning, insomnia) and I’d love to safely support my adrenals. In these email exchanges on cortisol ray mentions pregnenolone, but says that progesterone would more directly ameliorate adrenal damage.
Also @ecstatichamster would love to know if you’re still taking pregnenolone, as I’ve read of your recent success with thyroid.