whatever
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- Aug 10, 2017
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Abstract
The present study describes the hair growth-promoting effects of sodium thiosulfate (STS), a widely used compound, in mice. STS accelerated hair growth in the "telogen model", suggesting that it stimulates telogen hair follicles to reenter the anagen phase of hairgrowth. In the same model, STS potentiated hair growth in an additive manner with minoxidil (MXD), a drug used for the treatment of androgenic alopecia. Furthermore, in the "anagen model", STS promoted hair growth, probably by promoting hair follicle proliferation. Since STS elevated the skin surface temperature, its hair growth-promoting activity may be partly due to vasorelaxation, similar to MXD. In addition, STS is known to generate a gaseous mediator, H2S, which has vasorelaxation and anti-inflammatory/anti-oxidative stress activities. Therefore, STS and/or provisionally its metabolite, H2S, may aid the hair growth process. Collectively, these results suggest that salts of thiosulfate may represent a novel and beneficial remedy for hair loss.
Calcification, inflammation, poor blood flow, Thiosulfate is calcium chelator, anti inflammatory, anti oxidative, vasorelaxant incrising blood flow, (STS elevated the skin surface temperature, its hair growth-promoting activity may be partly due to vasorelaxation)
I am thinking to make a 10% solution in 40% ethanol, the rest water, and apply it on the scalp... the only one thing that we have to see ... if is safe to apply it on the scalp for months ..
What do you think? We should give it a try .
Thiosulfate promotes hair growth in mouse model. - PubMed - NCBI
There is evidence that onion juice for example.. grows hair in alopecia... maybe because of the sulfurs that onions contains ..
About the safety of thiosulfate:
Evaluation of adverse effects:
To exclude the possibility that the external applica- tion of STS to the skin impairs systemic health, we measured the deep body temperature at week 14 in the telogen model by recording rectal temperature twice a day (at 09:00 and 15:00). No significant differences were seen between any of the treatment groups and the control group (Supplemental Table 10), thereby excluding potential noxious events, including inflammation via external STS treatments. Blood biochemistry data suggested no adverse effects of STS (Supplemental Table 11). Moreover, we found no structural abnormalities of the skin in the STS- treated groups of the anagen model by histological examination.
They say: Blood biochemistry data suggested no adverse effects of STS , but it's a clear increase of CPK Creatine phosphokinase , in blood , in STS model compared with Control model. Now, I don't know the possible effects of this increased CPK in humans , and possible side effects .
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