inflammation

I came across this interesting article* today. There's something appealing in the idea that awful things like depression, and potentially anxiety, could ultimately come down to inflammation caused by seed oils and such, perhaps because, if true, it should be a simple problem to overcome. Stop...

[ moderator edit: threads merged ] Bacteria lurking in blood could be culprit in countless diseases

Saturated Fats Damage Health by Promoting Inflammation

Another one in the series of endotoxin antagonism featuring so far vitamins D and B2. Vitamin B2 (riboflavin) Is Endotoxin Antagonist Vitamin B2 Remarkably Effective Against Endotoxin, Sepsis, And Other Bacterial Infections Vitamin D Is Endotoxin (LPS / TLR4) Antagonist, May Treat LPS-linked...

The activation of TLR by various substances like endotoxin, ethanol / alcohol, opioids, SSRI, etc is involved in the pathogenesis of many conditions, especially IBD, colon cancer, periodontal disease, etc. There are very few effective endotoxin antagonists in clinical use, which is unfortunate...

I like this study for a number of reasons. First, it validates the idea that the patient knows quite well when something is plaguing them despite the current approach to ignore completely self-reported symptoms. Second, it confirms the connection between stress and inflammation, and viral...

Most people here know Peat's opinion about opioids due to their effects on histamine, estrogen, and promoting tissue growth. A few weeks ago I posted a link in regards to the so-called "endotoxin receptor" known as TLR4, and how opioids are the main class of substances that activate that...

Similar to my other post on blocking serotonin as a way to reverse fibrosis, the truth about what works and what doesn't in medicine is slowly coming out. After decades of denying that aspirin may have any effects on treating cancer, apparently clinical trials are about to begin with aspirin for...

BPH is a very common problem, apparently affecting more than 70%of men over 50. Ray has said in some email exchanges that prostatitis and BPH are linked with endotoxin. I was not able to find much published research on the topic but this new study finally makes that claim. What is more...

I think this is a very persistent myth and one that is reigning supreme on all forums except this one. Even here, we occasionally get challenged and statements referring to this flawed idea. Here is something that will hopefully clarify why the steroid "steal" is a flawed idea. Among the more...

I posted several studies recently about maternal hypothyroidism and stress being linked to autism, as well as the use of serotonin antagonist to reverse autism pathology in an animal model. This study adds more weight to the serotonin-autism connection. It showed that triggering flu-like...

I have always been suspicious of the massive GERD drug market and the fact that despite them being the most prescribed drugs in the USA, the incidence of esophageal cancer (which they were designed to prevent) has been rising with scary speed. The raw data from the clinical trials on PPI drugs...

LRP5 - Wikipedia im so interest to find any info on how increase Lrp5(it strongly inhibit gut serotonin release) , only thing i found that upregulates the synthesis of it is vitamin D, and also Cholesterol. but who knows, maybe serotonin lowering effect of salt works through this pathway...

Treatment of mast cells with carbon dioxide suppresses degranulation via a novel mechanism involving repression of increased intracellular calcium levels. Results from this study provide the first evidence of a unique regulatory mechanism by which CO₂ inhibits mast cell degranulation and...

As many people on the forum know, the primary driver of inflammation in humans is the metabolism of arachidonic acid into various inflammatory mediators like prostaglandins, leukotrienes, and tromboxanes. If you remove arachidonic acid, about 90% of the inflammatory response goes away. However...

The phosphodiesterase inhibitors pentoxifylline and rolipram suppress macrophage activation and nitric oxide production in vitro and in vivo. - PubMed - NCBI Abstract We studied the effects of the phosphodiesterase inhibitors pentoxifylline (PTX) and rolipram (ROL) on nitric oxide (NO)...

Ray has been writing about this for decades. However, the official Wikipedia page still says that the cause of endometriosis is currently unknown and probably involved genetics. Endometriosis - Wikipedia, the free encyclopedia "...The cause is not entirely clear.[2] Risk factors include having...

Ray has written so much of the effects of stress on health and specifically on how chronic stress promotes energetic dysfunction and tumor formation/growth/spread. However, up until a year ago there was very little "official" research to back up his views. This study does just that, and it shows...

Hello all I found this study extremely interesting. They say it reduces inflammation unless I read it wrong. Bifidobacterium infantis 35624 modulates host inflammatory processes beyond the gut Beachbum

This thread is similar to the one I created for emodin and in support of the Lapodin supplement I released. Lapodin: Lapodin - Dietary Supplement With Beta-lapachone And Emodin | Ray Peat Forum Emodin: Amazing Medicinal Properties Of Emodin | Ray Peat Forum The purpose of this thread is to...