Mauritio
Member
- Joined
- Feb 26, 2018
- Messages
- 5,669
That's exactly what I was wondering about . Thanks.In contrast, the first study in the original post showed that serotonin receptor antagonism occurred at doses about 2-fold higher than LSD, which is used in microgram amounts, which achieve low-nanomolar concentrations in-vivo. So, roughly a factor of 1,000 as a buffer/preferentiality.
I also found a study showing 6Meo/ 6OMe harmalan has low binding affinities for 5HT2c and even lower affinity for 5HT2a receptors ,which explains its low hallucinogenic properties.
Although I'm not sure what the (S.E.M.) in braces means.