DaveFoster- Do you think children's benadryl liquid is ok to take daily at bedtime at a dose of 10mL? I am needing it to control itching from eczema. Are there known cumulative effects even in low doses, and at what point would I know? I don't like the idea of anticholinergics if it's not the body's natural way to balance things. Any help would be appreciated.Dyphenhydramine has significant serotonergic effects in dosages of ~150 mg or higher.