This term is used a lot from folks like Ben Greenfield and Paul Saladino as ways to explain why they think some do better on low carb vs high carb and vice versa. For example, my practitioner just recently saw my blood work (high insulin, high blood sugar) since starting higher carbs and explained that this could be due to my FUT2 gene expression being down regulated. There do seem to be some studies that certain genes can be medically relevant and alter ones ability to process certain macros better than others. Anyone have experience with this? My practitioner seems to think that based on my genes and blood work, I should go back to low carb. I may just do so...