Sheila said:Hello,
I was chatting to a friend about candida like you do, a woman who has made a wondrous improvement to her chronic health issues by following Peat's understandings. Since it is a yeast, and some yeasts produce various forms of B3 (niacin and niacinamide) we wondered whether candida was some kind of symbiotic helper (even if last ditch!) for those with low metabolism. The - albeit potentially slightly crazy - theory being the host can't make/get the B3 it needs because it is so compromised energetically, so the fungus turns up to do it for the host, with unfortunately some very unpleasant side effects. Brewers yeast and certain (edible) mushrooms are high in B3 too but I have no real idea how all these spore critters are really related.
Nor if B3 production is a 'mushroom/fungi/yeast' general thing.
[As an aside, in Sugar Myths 2 which is just in for verification, and will be up shortly, Peat says:
"....and the thyroid hormone is what basically distinguishes humans from fungus and bacteria and such; the higher development of the brain goes, the more oxidative energy production is needed. " ]
Anyway, well done for reading this far, even if your eyes are rolling. Because the next bit, is that Niacinamide has been trialled as a cure for candida via modulation of a specific gene expression (I think) of the yeast.
http://www.sciencedaily.com/releases/20 ... 141617.htm
Journal Reference:
Hugo Wurtele, Sarah Tsao, Guylaine Lépine, Alaka Mullick, Jessy Tremblay, Paul Drogaris, Eun-Hye Lee, Pierre Thibault, Alain Verreault, Martine Raymond. Modulation of histone H3 lysine 56 acetylation as an antifungal therapeutic strategy. Nature Medicine, 2010; 16 (7): 774 DOI: 10.1038/nm.2175
Now, I don't know about that, but what if by giving the niacinamide there is no more reason for the yeast to be in the loop, at least at overgrowth levels? And the host gets help with energy production and hopefully everyone's happy. (I see this as akin to balanced sugar levels keeping candida present but nicely quiescent.)
Just a thought, does supplementary niacinamide kill it or does it make it no longer required?
Feel free to tell me where the logic bomb is. Or that I am hypoglycaemic or must just get out more.
It might just be useful without the above conjecture to help some of you with this issue if you've not already tried and tested this avenue.
Bye for now
Sheila
Sheila-
Very interesting on both views.
The Lita Lee idea--that Candida is not the cause of the problem,
but rather an effect of some underlying issue--
your perpectives may be harmonious with that general way of thinking about it.
This whole gut microbiome thing is way complicated.
The more I research it, the more complicated.