Travis
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- Jul 14, 2016
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I did read about that in the article above, and this apparently was just as good for cancer. But since it doesn't inhibit polyamine formation directly, I'm somewhat confused on how it does so.how about Se-Methyl L-Selenocysteine does it work particucarly for detox for gluthation.
Does it boost the gluthation levels less effective then selenomethionine and also does brazil nuts contain selenomethionine or which plant does contain good amounts ?
The S‐linked methyl group isn't a particularly strong bond. These bonds are broken and formed all the time within the body; a classic example is S‐adenoslymethionine or pyruvate decarboxylase. In the body, acetyl groups and acyl chains are commonly transferred from sulfur to sulfur.
So I think you could expect glutathione to be made from this, after demethylation, but a glutathione with selenium instead of sulfur. I think you could also expect Se‐glutathione to have different properties than glutathione; inhibiting glutathione has been thought of as a line‐of‐attack against cancer cells in the past.
Glutathione, like spermine, is necessary for cell division; glutathione transfers to the nucleus before mitosis, and this is a prerequisite for cell division. Methylglyoxal also 'inhibits' glutathione as it spontaneously bonds to its sulfur. The inhibition of glutathione is actually how Thornally had explained methylglyoxal's anticancer effects, although Koch seemed to explain it through polyamines.
So I think understand how (CH₃)‐Se‐cysteine works would be similar to understanding how glutathione works.. .