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I have found some articles about nano particles which deliver vaccines through nasal delivery. Maybe this is why they say they must shove a super long cotton tip up your nose so they can deliver these nano particles. Wouldn't saliva from the inside of the mouth like a DNA test suffice?
I am interested to hear what people on this forum think about this?
Exploring the Potential of Carbon Dots to Combat COVID-19 - PubMed
I am interested to hear what people on this forum think about this?
Inspired by Parasitic Worms, Researchers Engineer Tiny Machines That Deliver Medicine Efficiently
"Theragrippers" are inspired by a parasitic worm that clamps onto its host's intestines. Inspired by a parasitic worm that digs its sharp teeth into its host’s intestines, Johns Hopkins researchers have designed tiny, star-shaped microdevices that can latch onto intestinal mucosa and release drug
scitechdaily.com
Development of a novel adjuvanted nasal vaccine: C48/80 associated with chitosan nanoparticles as a path to enhance mucosal immunity - PubMed
In a time in which mucosal vaccines development has been delayed by the lack of safe and effective mucosal adjuvants, the combination of adjuvants has started to be explored as a strategy to obtain potent vaccine formulations. This study describes a novel adjuvant combination as an effective...
pubmed.ncbi.nlm.nih.gov
Development of nanoparticle-delivery systems for antiviral agents: A review - PubMed
The COVID-19 pandemic has resulted in unprecedented increases in sickness, death, economic disruption, and social disturbances globally. However, the virus (SARS-CoV-2) that caused this pandemic is only one of many viruses threatening public health. Consequently, it is important to have...
pubmed.ncbi.nlm.nih.gov
Hydrogel nanoparticles and nanocomposites for nasal drug/vaccine delivery - PubMed
Over the past few years, nasal drug delivery has attracted more and more attentions, and been recognized as the most promising alternative route for the systemic medication of drugs limited to intravenous administration. Many experiments in animal models have shown that nanoscale carriers have...
pubmed.ncbi.nlm.nih.gov
Nanoparticles for nasal vaccination - PubMed
The great interest in mucosal vaccine delivery arises from the fact that mucosal surfaces represent the major site of entry for many pathogens. Among other mucosal sites, nasal delivery is especially attractive for immunization, as the nasal epithelium is characterized by relatively high...
pubmed.ncbi.nlm.nih.gov
Nanoparticulate systems for nasal delivery of drugs: a real improvement over simple systems? - PubMed
This review discusses the possible benefits of using nanoparticles for nasal delivery of drugs and vaccines. It considers the various factors affecting particle transport across the nasal tissue. The evidence for the improved transport of drugs, such as peptides and proteins, across the nasal...
pubmed.ncbi.nlm.nih.gov
Pharmaceutical aspects of intranasal delivery of vaccines using particulate systems - PubMed
The nasal route offers a promising opportunity for the delivery of vaccines. This review analyses the opportunities and novel delivery strategies based on particulate systems for the nasal delivery of vaccines, including liposomes, proteosomes, virosomes, nano- and microparticulate systems, with...
pubmed.ncbi.nlm.nih.gov
Nanoemulsion-based intranasal drug delivery system of saquinavir mesylate for brain targeting - PubMed
The central nervous system (CNS) is an immunological privileged sanctuary site-providing reservoir for HIV-1 virus. Current anti-HIV drugs, although effective in reducing plasma viral levels, cannot eradicate the virus completely from the body. The low permeability of anti-HIV drugs across the...
pubmed.ncbi.nlm.nih.gov