- Joined
- Oct 30, 2015
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Good findHypothyroidism causes low FAD as the conversion steps from free riboflavin to FMN and FAD are thyroid-dependent. So even with sufficient intake of dietary riboflavin low FAD can show up. Maybe another hint on why fasting is detrimental to thyroid health.
Riboflavin metabolism in the hypothyroid human adult - PubMed
It had been shown that thyroxine regulates the conversion of riboflavin to riboflavin mononucleotide and flavin adenine dinucleotide (FAD) in laboratory animals. In the hypothyroid rat, the flavin adenine dinucleotide level of the liver decreases to levels observed in riboflavin deficiency. We...pubmed.ncbi.nlm.nih.gov