Hello members,
I am 32 years old male, got a health checkup done recently and below are the abnormal values
Lymphocytes absolute count: 3.12 * 10^3/ul (range: 1.0 to 3.0)
LYMPHOCYTE PERCENTAGE : 49.8 % (range 20-40)
TOTAL RBC : 6.11 * 10^6/ul (range: 4.5 to 5.5)
MCV : 77.9 fL (range: 83-101)
MCH: 25.5 pq (range: 27-32)
RDW: 14.7% (range: 11.6-14)
PLATELET TO LARGE CELL RATIO(PLCR) : 17.9% (range: 19.7-42.4)
Netrophils, other blood cells, Hemoglobin, Hematocrit are in range
Homocysteine is in range, HsCRP is 0.3mg/L - in range, PSA is in range. All liver panel are normal. Serum Uric acid, Creatinine, BUN are in range. estimated GFR (based on CKD-EPI) is 110 mL/min/1.73 m2
CYSTATIN C : 1.32 mg/dl (range: <=1.30 mg/dl)
Vitamin D3: 17.59 ng/ml deficiency (range: 30-100 ng/dl)
Iron: 151 ug/dl (range: 65-175)
TOTAL IRON BINDING CAPACITY (TIBC) : 326 ug/dl (range: 225-535)
% TRANSFERRIN SATURATION : 46.32 % (range: 13-45)
FERRITIN : 204.6 ng/ml (range: 22-322)
TESTOSTERONE: 142.42 ng/dl (range: 164.94-753.38)
LACTATE DEHYDROGENASE: 257 u/L (range: 120-246)
Note: I am not living at an elevation and I don't use steroids.
Based on these there are many possibilities and I don't know where to start and hence request help
1. I could be having Hypoxia, driving RBC high which will push LDH high since RBCs use LDH but that cannot explain high Cystatin C which is maintained by Kidneys.
2. High Cystatin C could be coming from high Lymphocyte count which are nucleated cells but not sure why my kidneys are not able to filter it
3. I was down with fever about a month back and recoved with antibiotics so not sure if the Lymphocyte count will stay elevated even after a month
4. High LDH, Cystatin C, high %Transferrin saturation could point to tissue damage and coupled with high RBC, Lymphocyctes could mean Lymphoma
6. Possible kidney damage from high Lymphocyte count which could explain high Cystatin C
Regardless, this is what I am planning to do
1. Get retested after a month but this time with complete blood peripheral smear, Bicarbonate, Ammonia, Ceruloplasmin along with whole abdomen Ultrasound
2. Supplement with Vitamin D3, Methylene blue, Red light daily, Vitamin K2, Vitamin A. I have already been taking Vitamin E, Energin (Vitamin Bs) along with 100 mg doses of Thiamine/Niacinamide spread across the day to stimulate PDH and lower lactate.
3. Drinking Cranberry juice to lower Iron. Ordered IP6 as well. Avoiding foods fortified with Iron
4. Activated Charcoal once or twice a week to deal it from endotoxin angle
5. Antihistamines like Cyproheptadine.
Please help me interpret these results and future course of action.
I am 32 years old male, got a health checkup done recently and below are the abnormal values
Lymphocytes absolute count: 3.12 * 10^3/ul (range: 1.0 to 3.0)
LYMPHOCYTE PERCENTAGE : 49.8 % (range 20-40)
TOTAL RBC : 6.11 * 10^6/ul (range: 4.5 to 5.5)
MCV : 77.9 fL (range: 83-101)
MCH: 25.5 pq (range: 27-32)
RDW: 14.7% (range: 11.6-14)
PLATELET TO LARGE CELL RATIO(PLCR) : 17.9% (range: 19.7-42.4)
Netrophils, other blood cells, Hemoglobin, Hematocrit are in range
Homocysteine is in range, HsCRP is 0.3mg/L - in range, PSA is in range. All liver panel are normal. Serum Uric acid, Creatinine, BUN are in range. estimated GFR (based on CKD-EPI) is 110 mL/min/1.73 m2
CYSTATIN C : 1.32 mg/dl (range: <=1.30 mg/dl)
Vitamin D3: 17.59 ng/ml deficiency (range: 30-100 ng/dl)
Iron: 151 ug/dl (range: 65-175)
TOTAL IRON BINDING CAPACITY (TIBC) : 326 ug/dl (range: 225-535)
% TRANSFERRIN SATURATION : 46.32 % (range: 13-45)
FERRITIN : 204.6 ng/ml (range: 22-322)
TESTOSTERONE: 142.42 ng/dl (range: 164.94-753.38)
LACTATE DEHYDROGENASE: 257 u/L (range: 120-246)
Note: I am not living at an elevation and I don't use steroids.
Based on these there are many possibilities and I don't know where to start and hence request help
1. I could be having Hypoxia, driving RBC high which will push LDH high since RBCs use LDH but that cannot explain high Cystatin C which is maintained by Kidneys.
2. High Cystatin C could be coming from high Lymphocyte count which are nucleated cells but not sure why my kidneys are not able to filter it
3. I was down with fever about a month back and recoved with antibiotics so not sure if the Lymphocyte count will stay elevated even after a month
4. High LDH, Cystatin C, high %Transferrin saturation could point to tissue damage and coupled with high RBC, Lymphocyctes could mean Lymphoma
6. Possible kidney damage from high Lymphocyte count which could explain high Cystatin C
Regardless, this is what I am planning to do
1. Get retested after a month but this time with complete blood peripheral smear, Bicarbonate, Ammonia, Ceruloplasmin along with whole abdomen Ultrasound
2. Supplement with Vitamin D3, Methylene blue, Red light daily, Vitamin K2, Vitamin A. I have already been taking Vitamin E, Energin (Vitamin Bs) along with 100 mg doses of Thiamine/Niacinamide spread across the day to stimulate PDH and lower lactate.
3. Drinking Cranberry juice to lower Iron. Ordered IP6 as well. Avoiding foods fortified with Iron
4. Activated Charcoal once or twice a week to deal it from endotoxin angle
5. Antihistamines like Cyproheptadine.
Please help me interpret these results and future course of action.