Does anyone know effective options to down regulate androgen receptors?
The androgen receptor deregulation seems to be the most accepted PFS theory.
Of particular interest, androgen receptor expression (AR) was found to be significantly higher in patients compared to controls, in the absence of differences in serum markers indicating AR activity or trinucleotide repeat variation. The authors suggested that AR overexpression in response to an androgen-deficient state may negatively affect multiple tissues throughout the body, could be responsible for the sexual symptoms of Post-Finasteride Syndrome, and - if overexpressed in other tissues - may be involved in other symptomatic domains, including cognitive symptoms.
@Hans You know how to do this?
The androgen receptor deregulation seems to be the most accepted PFS theory.
Of particular interest, androgen receptor expression (AR) was found to be significantly higher in patients compared to controls, in the absence of differences in serum markers indicating AR activity or trinucleotide repeat variation. The authors suggested that AR overexpression in response to an androgen-deficient state may negatively affect multiple tissues throughout the body, could be responsible for the sexual symptoms of Post-Finasteride Syndrome, and - if overexpressed in other tissues - may be involved in other symptomatic domains, including cognitive symptoms.
Differential Gene Expression in Post-Finasteride Syndrome Patients — PFSNetwork.org
Evidence of gene expression correlating with observed biologic differences, including significant Androgen Receptor overexpression, was reported in a landmark investigation of patients with post-finasteride syndrome.
www.pfsnetwork.org
@Hans You know how to do this?