Brooks Esq.
Member
Thank you for the warning. I made it a point to purchase the one from Life Extensions since they are a reputable companyHey good luck and report how you do on it.
Try to research the best and purest product and read peoples experiences.
Just a few heads up:
RP" From the symptoms people are describing, I think some of the pregnenolone being sold is contaminated. I ate 3000 mg per day 35 years ago, when only one big company was making it.
The pregnenolone I had was made from wild yam diosgenin by Syntex, which had the best equipment and the best chemists. There are dozens of companies making it now, and like most other products, it’s being made without the best available methods which would be too expensive."
RP: "I haven’t recommended pregnenolone use for several years, since I started hearing about reactions that could only be caused by major impurities."
RP: "I started using pregnenolone from Sigma Chemical, then got it by the kilogram from the Syntex factory in Mexico. When they stopped making it, I got a few kilos from European companies, but when they stopped making it, I found that pregnenolone from other sources produced hormonal effects that shouldn’t be pregnenolone, so I stopped using it; that was some time in the ‘90s. Pure pregnenolone never produced hormonal effects in either human or animal studies. Minor producers don’t have the resources of the giants to produce extreme purity."
Q: "I was wondering if you have much knowledge about the manufacturing methods of pregnenolone? What would it take to produce something that matches the quality of the Syntex produced pregnenolone you have spoken of?"
RP: "I think it would take someone who worked at that factory at the time, since the chemists are always fiddling with their processes. Vitamins C and E, and probably others, have gone through many phases, with changing biological effects."
Q: I mailed Ray about the issues I was having with pregnenolone, namely sadness, irritability, major hair loss, insomnia, weight gain
RP: Excipients or impurities in capsules can cause symptoms, by irritating the intestine. In animal studies (and in myself), extremely large doses didn't have any more effects than minimal doses. It's possible to eliminate some of the impurities by mixing it with warm vitamin E, and after stirring it, allowing it to settle, and using only what dissolved in the vitamin E.
Q:Then I asked if there's no way it can convert to excess estrogen or some other stress related hormone, under certain circumstances, like not getting enough protein or sugar, or some other nutrient, or adequate light…
RP: I haven't heard of a situation like that; I'll see if I can find any information relating to that possibility.