Travis
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- Joined
- Jul 14, 2016
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I can chime in and say eye colour is definitely related to neurotransmitters, norephiprene being hazel, dopamine and serotonin being blue.
Any play between colours is from my perspective showing your neurotransmitter ratio.
I was just reading about that. You are onto something.
Some pigments, like melanin, are actually polymerized indoles made from dopachrome and adrenochrome (and perhaps others), metabolites of adrenaline and dopamine.
Not many people realize how closely adrenaline and dopamine can become indoles; a non-intuitive ring condensation occurs:
Adrenochrome is red in color. Dopachrome and adrenochrome polymerize together forming pigments. Below is melanin.
Addison's Disease is characterized by both an adrenal malfunction and a pigmentation disorder of the skin. Schizophrenics are thought by Dr. Osmond and Dr. Hoffer to have a difficult time reducing adrenochrome to leuco-adrenochrome (colorless). An excess of adrenochrome is thought to produce the very effects of schizophrenia. Schizophrenics maintain colored hair for longer than controls, and injections of adreochrome have been shown to produce a "freckle" at the injection site, showing that catecholamines have an effect on pigmentation through their subsequent formation of indoles.
You might expect the color of the pigments to change with variations in the types of indoles present, be they seratonin, melatonin, adrenochrome, or dopachrome.
Another metabolite of adrenaline is adrenolutin, which is green.
Read all about Dr. Hoffer and Dr. Osmond's experiments with adrenochrome and adrenolutin here: THE HALLUCINOGENS [p.275−441]