Mauritio
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- Feb 26, 2018
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In this study they looked at the effect of PUFA on liver health and Vitamin E's capibility to prevent liver damage.
They fed mice a diet high in linoleic acid, low in linoleic acid or high in linoleic acid and supplemented with Vitamin E.
The results are remarkable: in many ways the Vitamin E was able to completely prevent the liver damage, even while the mice were still eating the high PUFA diet. Exactly what Peat has said for years.
They dont specify which kind of Vitamin E they used, but the VIT-E/PUFA (mg/g) was 1.9 . So if you eat 5g of PUFA per day you would need about 15 IU of Vitamin E per day, if you want to replicate this study.
- Vitamin E dramatically lowered serum triglycerides, FFAs and liver triglycerides:
Serum ALT was lowered a lot and Malondialdehyde was lowered to levels even below the control diet!
- Ability of high fat diet to induce liver pathology correlates with the level of linoleic acid and Vitamin E in the diet
They fed mice a diet high in linoleic acid, low in linoleic acid or high in linoleic acid and supplemented with Vitamin E.
The results are remarkable: in many ways the Vitamin E was able to completely prevent the liver damage, even while the mice were still eating the high PUFA diet. Exactly what Peat has said for years.
"Taken together, our results suggest that a high level of LA and a low ratio of VIT-E/PUFA in HFD can contribute significantly to metabolic abnormalities and hepatic injury."
They dont specify which kind of Vitamin E they used, but the VIT-E/PUFA (mg/g) was 1.9 . So if you eat 5g of PUFA per day you would need about 15 IU of Vitamin E per day, if you want to replicate this study.
- Vitamin E dramatically lowered serum triglycerides, FFAs and liver triglycerides:
Serum ALT was lowered a lot and Malondialdehyde was lowered to levels even below the control diet!
- Ability of high fat diet to induce liver pathology correlates with the level of linoleic acid and Vitamin E in the diet
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