Yes, I agree with all that.It can help some people temporarily. In the end it is not a permanent solution, no drug is. It will help those with excess histamine and high serotonin levels the most. The rest it will do nothing or make them worse.
I never understood the use of antihistamines unless you have severe allergic reactions and chronically high, insane histamine levels and the symptoms to go along with it. That is the only reason I would ever recommend its temporary use. In that case it should be used while the diet and micronutrient intake is fixed and optimized and the histamine levels are brought down to more controllable levels through use of methyl donors such as TMG.
Then it should be stopped to allow the homeostasis to return because make no mistake it is not normal homeostasis to depend on an antihistamine and blocking all these receptors that cypro blocks is not good for the body in the long run. It should not be taken while the appropriate steps to lower histamine levels and promote healthy adrenal activity are not being taken. Its like treating someone with ADHD with just adderall and never taking the necessary steps through diet and lifestyle to make it so not only could their medication work better but eventually they won't need it.
I kind of 'think out loud" as I wrote to someone else on here - I probably should word things more carefully - i.e. "i don't understand the rationale for the cypro" - other than for the high histamine... or something like that :) It probably doesn't matter anyway :) . More appropriate - would I want to take this?
Worded a bit differently - there is no magic pill, I'm too tired now to write eloquently - but you put that so well re: manipulating receptors and neurotransmitters for long periods of time - because physiology is so intricate - changing one thing always creates a domino effect.
And yes, adderall - it sure would be nice if that was done or is possible.