Interesting one right here.
Crocus sativus L. Versus Methylphenidate in Treatment of Children with Attention-Deficit/Hyperactivity Disorder: A Randomized, Double-Blind Pilot Study - PubMed - "Short-term therapy with saffron capsule showed the same efficacy compared with methylphenidate. Nevertheless, larger controlled studies with longer treatment periods are necessary for future studies."
Effectivity of Saffron Extract (Saffr’Activ) on Treatment for Children and Adolescents with Attention Deficit/Hyperactivity Disorder (ADHD): A Clinical Effectivity Study - "In conclusion, this pilot study presents evidence of the efficacy and safety of saffron extract compared to methylphenidate in a sample of children and adolescents with ADHD. Although comparable in general terms, saffron tends to be more effective for hyperactivity symptoms, while methylphenidate is more effective for inattention symptoms. Furthermore, both treatments improved the number of sleeping hours, but only saffron made it easier to fall asleep."
https://www.sciencedirect.com/science/article/abs/pii/S2212958822000027 - This one is saf+mph - "In this randomized, double-blind, placebo-controlled clinical trial, we demonstrated that saffron combination therapy with Ritalin can effectively improve symptoms of patients with ADHD."
Surprised I haven't seen this posted here. I am personally very interested in ADHD, I used to have it(54mg concerta daily) but I was able to reverse it through several means. I have not tried saffron.
The reason I say saffron is more effective is because it's undoubtedly much safer long term, and does not have to be cycled on and off, like methylphenidate does. Taking stimulants 7 days a week is a surefire way to build tolerance and dependence. I suspect the saffron has less to do with direct dopamine/catecholamine action and more to do with enhancing metabolism and reducing inflammation of the brain. This is evidenced by, "Although comparable in general terms, saffron tends to be more effective for hyperactivity symptoms, while methylphenidate is more effective for inattention symptoms." from second study.
One of the studies only used 30mg a day, so it's definitely an affordable treatment.
Crocus sativus L. Versus Methylphenidate in Treatment of Children with Attention-Deficit/Hyperactivity Disorder: A Randomized, Double-Blind Pilot Study - PubMed - "Short-term therapy with saffron capsule showed the same efficacy compared with methylphenidate. Nevertheless, larger controlled studies with longer treatment periods are necessary for future studies."
Effectivity of Saffron Extract (Saffr’Activ) on Treatment for Children and Adolescents with Attention Deficit/Hyperactivity Disorder (ADHD): A Clinical Effectivity Study - "In conclusion, this pilot study presents evidence of the efficacy and safety of saffron extract compared to methylphenidate in a sample of children and adolescents with ADHD. Although comparable in general terms, saffron tends to be more effective for hyperactivity symptoms, while methylphenidate is more effective for inattention symptoms. Furthermore, both treatments improved the number of sleeping hours, but only saffron made it easier to fall asleep."
https://www.sciencedirect.com/science/article/abs/pii/S2212958822000027 - This one is saf+mph - "In this randomized, double-blind, placebo-controlled clinical trial, we demonstrated that saffron combination therapy with Ritalin can effectively improve symptoms of patients with ADHD."
Surprised I haven't seen this posted here. I am personally very interested in ADHD, I used to have it(54mg concerta daily) but I was able to reverse it through several means. I have not tried saffron.
The reason I say saffron is more effective is because it's undoubtedly much safer long term, and does not have to be cycled on and off, like methylphenidate does. Taking stimulants 7 days a week is a surefire way to build tolerance and dependence. I suspect the saffron has less to do with direct dopamine/catecholamine action and more to do with enhancing metabolism and reducing inflammation of the brain. This is evidenced by, "Although comparable in general terms, saffron tends to be more effective for hyperactivity symptoms, while methylphenidate is more effective for inattention symptoms." from second study.
One of the studies only used 30mg a day, so it's definitely an affordable treatment.
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