Candeias
Member
- Joined
- Apr 29, 2018
- Messages
- 220
Cyproheptadine
Cyproheptadine Prevents / Reverses Soft Tissue Calcification
"Human equivalent dose was about 12mg daily, duration was just 4 days. Cyproheptadine prevented AND reversed soft tissue calcification by acting as an anti-heparin agent, which is similar to what vitamin K2 does.
EFFECT OF CYPROHEPTADINE ON A TOPICAL CALCIFICATION IN THE RAT - PubMed
""...In the rat, cyproheptadine prevents the soft-tissue calcification elicited by various mast-cell depletors at their subcutaneous injection site. This action does not appear to result from the anti-histaminic anti-serotonin properties of cyproheptadine, which showed in addition an in vitro anti-heparin effect.""
@haidut
Topic: Cyproheptadine And Vitamin D Seem To Go Very Well Together
@lampofred
Magnesium (and reduction of phosphorous)
Treatment of soft tissue calcifications with magnesium
Dietary magnesium supplementation prevents and reverses vascular and soft tissue calcifications in uremic rats
Acute Induction of Soft Tissue Calcification with Transient Hyperphosphatemia in the KK Mouse by Modification in Dietary Contents of Calcium, Phosphorus, and Magnesium
"(...)Addition of magnesium or reduction of phosphorus in the diet completely prevented the development of all these changes(...)The present findings suggest that relative deficiency in magnesium is mainly responsible for the development."
Vitamin K
The Inhibitory Roles of Vitamin K in Progression of Vascular Calcification
"(...)Matrix Gla protein (MGP) is a major inhibitor of soft tissue calcification and contributes to preventing both intimal and medial vascular calcification. Vitamin K may also inhibit progression of vascular calcification by enhancing the activity of MGP through facilitating its γ-carboxylation."
Famotidine
Famotidine suppresses osteogenic differentiation of tendon cells in vitro and pathological calcification of tendon in vivo
"(...)Famotidine administration suppressed calcification in the Achilles tendon of ttw mice, a mouse model of ectopic ossification. These data suggest that famotidine inhibits osteogenic differentiation of tendon cells in vitro, and this inhibition may underlie the anti-calcification effects of the drug in vivo."
Famotidine Lowers PTH By Almost 50%
If you know of more accessible substances, please post.
Cyproheptadine Prevents / Reverses Soft Tissue Calcification
"Human equivalent dose was about 12mg daily, duration was just 4 days. Cyproheptadine prevented AND reversed soft tissue calcification by acting as an anti-heparin agent, which is similar to what vitamin K2 does.
EFFECT OF CYPROHEPTADINE ON A TOPICAL CALCIFICATION IN THE RAT - PubMed
""...In the rat, cyproheptadine prevents the soft-tissue calcification elicited by various mast-cell depletors at their subcutaneous injection site. This action does not appear to result from the anti-histaminic anti-serotonin properties of cyproheptadine, which showed in addition an in vitro anti-heparin effect.""
@haidut
Topic: Cyproheptadine And Vitamin D Seem To Go Very Well Together
@lampofred
Magnesium (and reduction of phosphorous)
Treatment of soft tissue calcifications with magnesium
Dietary magnesium supplementation prevents and reverses vascular and soft tissue calcifications in uremic rats
Acute Induction of Soft Tissue Calcification with Transient Hyperphosphatemia in the KK Mouse by Modification in Dietary Contents of Calcium, Phosphorus, and Magnesium
"(...)Addition of magnesium or reduction of phosphorus in the diet completely prevented the development of all these changes(...)The present findings suggest that relative deficiency in magnesium is mainly responsible for the development."
Vitamin K
The Inhibitory Roles of Vitamin K in Progression of Vascular Calcification
"(...)Matrix Gla protein (MGP) is a major inhibitor of soft tissue calcification and contributes to preventing both intimal and medial vascular calcification. Vitamin K may also inhibit progression of vascular calcification by enhancing the activity of MGP through facilitating its γ-carboxylation."
Famotidine
Famotidine suppresses osteogenic differentiation of tendon cells in vitro and pathological calcification of tendon in vivo
"(...)Famotidine administration suppressed calcification in the Achilles tendon of ttw mice, a mouse model of ectopic ossification. These data suggest that famotidine inhibits osteogenic differentiation of tendon cells in vitro, and this inhibition may underlie the anti-calcification effects of the drug in vivo."
Famotidine Lowers PTH By Almost 50%
If you know of more accessible substances, please post.
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