tankasnowgod
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A really impressive study, both for how long it went, and the results it obtained. It followed men taking Testosterone Therapy injections (1000mg once every twelve weeks), and men who were offered this therapy, but declined. The results are not only "drastic," as the following article says, but long term, as the longer the study went on, the more weight was lost in the Obese group, with no rebound sort of effect to baseline. The Overweight group also lost weight over 7 years, and then appears to mostly plateau at a new, lower weight. As far as "Losing Weight and Keeping it Off," this study does incredibly well in both of those groups.
Looking at the study, it would appear that very little weight loss occurred in the first year of injections. It seemed that it really started to occur in the second year, and keep on going over the course of the study.
The graphs showing the loss in weight and waist circumfrence-
The same group of researchers also appeared to post the results at the five year mark of the study-
Now, 1000mg injections every 12 weeks isn't the greatest dosing schedule, and it doesn't appear that any attempt was made to control estrogen with AI's or other drugs, T undecanoate was used, and there was no attempt made to monitor or supplement other hormones, like DHT or DHEA. Still, with all that being said, many Obese men were able to drop 50 pounds (or more in some cases), and keep it off and/or keep losing weight for a 7 to 11 year period, making it one of (if not the) most impressive studies ever conducted involving long term weight loss.
Testosterone injections 'can trigger drastic weight loss' in obese men
Men in Germany saw their weight drop by 4st and 3lbs (27kg) over a decade after getting testosterone jabs. Those who opted against the therapy saw their weight increase by almost a stone (6kg).
www.dailymail.co.uk
Testosterone injections can trigger drastic long-term weight loss in obese men, a German study has found. Men with an average weight of 18 stone (114kg) saw their weight drop by 4st and 3lbs (27kg) over a decade while having the jabs every three months as part of a study. Their body mass index (BMI) went from the 'severely obese' category, of 36.8, to 'overweight', at 28.8, just four points off the healthy weight range. In comparison, men who were not given the testosterone therapy saw their weight increase by almost a stone each (6kg).
Looking at the study, it would appear that very little weight loss occurred in the first year of injections. It seemed that it really started to occur in the second year, and keep on going over the course of the study.
Differential effects of 11 years of long-term injectable testosterone undecanoate therapy on anthropometric and metabolic parameters in hypogonadal men with normal weight, overweight and obesity in comparison with untreated controls: real-world data
Obesity is a chronic disease, warranting long-term medical intervention. We evaluated effects of testosterone (T) therapy (Th) in men with T deficiency with normal weight, overweight and obesity on anthropometric and metabolic parameters, compared with ...
www.ncbi.nlm.nih.gov
Results
Long-term TTh in hypogonadal men, irrespective of weight at baseline, produced improvements in body weight, waist circumference (WC) and body mass index (BMI). Furthermore, TTh decreased fasting blood glucose and HbA1c and improved lipid profiles. Gradual decreases in blood pressure (systolic and diastolic) and pulse pressure occurred in men treated with T in each group. Marked reductions in mortality and major cardiovascular events were recorded in men receiving TTh.
Conclusions
Our findings demonstrate that TTh produces reductions in weight, WC, and BMI. There were 77 (19.5%) deaths in the untreated groups and 23 (5.4%) in the T-groups. Based on these findings we suggest that long-term TTh in overweight and obese hypogonadal men produces progressive and sustained clinically meaningful weight loss and that TTh may contribute to reductions in mortality and incident major adverse cardiovascular events.
The graphs showing the loss in weight and waist circumfrence-
The same group of researchers also appeared to post the results at the five year mark of the study-
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onlinelibrary.wiley.com
Now, 1000mg injections every 12 weeks isn't the greatest dosing schedule, and it doesn't appear that any attempt was made to control estrogen with AI's or other drugs, T undecanoate was used, and there was no attempt made to monitor or supplement other hormones, like DHT or DHEA. Still, with all that being said, many Obese men were able to drop 50 pounds (or more in some cases), and keep it off and/or keep losing weight for a 7 to 11 year period, making it one of (if not the) most impressive studies ever conducted involving long term weight loss.