M
marikay
Guest
@haidut is theanine (200 mgs) safe to take before sleep? Or is suppressing cortisol through supplements not a good idea while sleeping?
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Cortisol is one of the most potent stimulators of aromatase. The estrogenic effects of green tea are probably due to the flavanols and EGCG contents, not theanine. GABA agonists like theanine are highly unlikely to raise estrogen, and will probably lower it. GABA agonists also (usually) upregulate 5-AR, which is another point against estrogen.
@Kim Many of my add symptoms has gone away in the last 2 weeks, and I think it is mainly because of taurine, theanine and glycine I take.
I don't take ritalin anymore. But for example, I'm for the first time in my life able to make habits, like brushing my teeth. You know, I would regularly brush my teeth, but it never felt like an habit to me, always I had to think about, and sometimes I would just forget.
Also, my sleep had been consistent, a bit late still, from 2 am to 10, but I can't remember a time that it had been so consistent.
My university work is so much organized, my work would be a chaotic mess. Even my handwriting has improved tremendously.
And so much more little things have changed, like for example, I put the cards of my wallet back in my wallet after I used them, I'm on time in my classes, I automatically make long term plans, I would never even think about what to do tomorrow, if I would not push myself.
Oh and I forget, my addictive behaviour has completely gone.
@dookie haha well, I must have had extremely low estrogen levels then, because I was a chaotic mess. I'm only glad that I have some more structure in my life.
But is ADD a sign low estrogen then? Because most people diagnosed with ADD that I know have the same problem. Unable to make habits, chaotic work, chaotic work place.
I highly doubt that. Cortisol will elevate estrogen more than anything, and with theanine, taurine and glycine, I'm sure my cortisol has dropped. Also my heart rate throughout the day is more stable, which I think means little cortisol is in play.
Wondering would it be safe to give my son theanine when he is currently on - 15mg of a amphetamines and 3mg of SSRI ? He is very very anxious/ self hurting and has OCD a ADD. Thank you for any help.
As I mentioned in my recent post on glycine lowering cortisol, I have suspected for a long time that inhibitory amino acids that act as GABA agonists will lower cortisol levels. The reason for this suspicion is that GABA agonist pharma drugs are used for treating the high cortisol of people with Cushing syndrome/disease. I posted an animal study some time ago showing that a hefty dose of theanine (1g+) lowered cortisol in animals. Now, this human study replicated the results and the even better news is that the dose is quite "low" compared to the animal study. The human dose used in this study was only 200mg and the effects were quite long lived as the cortisol lowering did not kick in until 3 hours after the amino acid was administered.
Anti-Stress, Behavioural and Magnetoencephalography Effects of an l-Theanine-Based Nutrient Drink: A Randomised, Double-Blind, Placebo-Controlled, ... - PubMed - NCBI
"...Due to evidence of violations to the assumption of normality in cortisol change, which were not corrected by transformation, non-parametric analysis of treatment effects was conducted. Results of Wilcoxon signed ranks tests showed no significant differences in cortisol change between active treatment compared to placebo 1 h post-dose (z = 1.28, p > 0.05, median cortisol response: placebo = −0.19, active = −0.02), but a significantly lower cortisol response 3 h post-dose for the active treatment visit (z = −1.98, p = 0.047, median cortisol response: placebo = 0.44, active = −0.09). A series of analyses were run in order to exclude the possibility that completion of the MEG component of the study immediately preceding this assessment differentially impacted cortisol responses. Mann–Whitney U-tests indicated that cortisol levels did not differ between MEG and non-MEG participants at the 3-h pre-MTF assessment at either treatment visit (placebo: z = −0.92, p = 0.372; active: z = −1.32, p = 0.197), nor did the MTF-related change in cortisol differ between MEG and non-MEG participants at either treatment visit (placebo: z = −0.92, p = 0.372; active: z = −0.33, p = 0.771) Change in cortisol for each assessment point is plotted for both treatment visits in Figure 2."
Attached is also a screenshot from the study that shows that theanine basically lowered stress-induced cortisol levels back to placebo status BEFORE stress.
Haidut-- is it possible that we might unintentionally raise adrenaline while reducing cortisol by theanine? Theanine has been the best sleep aid for me for months. The reason I am asking is that in the last week or so I have significantly been suffering from hyperventilation and hard time controlling it with supplements. I have hearth palpitations and a bit hard time staying asleep. I have been thinking as what has changed, what might be causing this. Recently, I had to increase my theanine dosage as I had a short trip to China. Suffering from jet lag, I used theanine extensively to sleep while I was there and also here back at home. Is it possible that as my body is under stress but cortisol is capped, it has to produce more adrenaline?
Obviously, there might be other things as well. I couldn't control my pufa and overall fat intake while on the trip among other things.
Cortisol is one of the most potent stimulators of aromatase. The estrogenic effects of green tea are probably due to the flavanols and EGCG contents, not theanine. GABA agonists like theanine are highly unlikely to raise estrogen, and will probably lower it. GABA agonists also (usually) upregulate 5-AR, which is another point against estrogen.
Do you think overall Green Tea is a net negative, or the estrogenic effects might be worth it? Theanine powder bothers my stomach / gives me weird farts.
I feel like pure theanine make my hair worst and I found a similar reaction on a hair loss forum. anyone has this experience ?
It's also interesting to see that high Gaba function is found in prostate cancer and promotes cell proliferation.
Expression of gamma-aminobutyric acid receptor (subtype A) in prostate cancer. - PubMed - NCBI
Hair loss and prostate cancer go hand in hand. Englishmen also seem to have a higher percentage of balding men and they ingest a lot of theanine. Japan do too but in the form of green tea that is anti-androgenic and probably counteracts theanine's effect. This is only an hypothesis of course but I'd really be curious if people here have this experience.
As I mentioned in my recent post on glycine lowering cortisol, I have suspected for a long time that inhibitory amino acids that act as GABA agonists will lower cortisol levels. The reason for this suspicion is that GABA agonist pharma drugs are used for treating the high cortisol of people with Cushing syndrome/disease. I posted an animal study some time ago showing that a hefty dose of theanine (1g+) lowered cortisol in animals. Now, this human study replicated the results and the even better news is that the dose is quite "low" compared to the animal study. The human dose used in this study was only 200mg and the effects were quite long lived as the cortisol lowering did not kick in until 3 hours after the amino acid was administered.
Anti-Stress, Behavioural and Magnetoencephalography Effects of an l-Theanine-Based Nutrient Drink: A Randomised, Double-Blind, Placebo-Controlled, ... - PubMed - NCBI
"...Due to evidence of violations to the assumption of normality in cortisol change, which were not corrected by transformation, non-parametric analysis of treatment effects was conducted. Results of Wilcoxon signed ranks tests showed no significant differences in cortisol change between active treatment compared to placebo 1 h post-dose (z = 1.28, p > 0.05, median cortisol response: placebo = −0.19, active = −0.02), but a significantly lower cortisol response 3 h post-dose for the active treatment visit (z = −1.98, p = 0.047, median cortisol response: placebo = 0.44, active = −0.09). A series of analyses were run in order to exclude the possibility that completion of the MEG component of the study immediately preceding this assessment differentially impacted cortisol responses. Mann–Whitney U-tests indicated that cortisol levels did not differ between MEG and non-MEG participants at the 3-h pre-MTF assessment at either treatment visit (placebo: z = −0.92, p = 0.372; active: z = −1.32, p = 0.197), nor did the MTF-related change in cortisol differ between MEG and non-MEG participants at either treatment visit (placebo: z = −0.92, p = 0.372; active: z = −0.33, p = 0.771) Change in cortisol for each assessment point is plotted for both treatment visits in Figure 2."
Attached is also a screenshot from the study that shows that theanine basically lowered stress-induced cortisol levels back to placebo status BEFORE stress.
Levant arabic men (egypt, syria, lebanon etc..) seem to get bald very early. They happen to be addicted to black tea. They also eat a lot of legumes and vegetable oils/olive oil.I feel like pure theanine make my hair worst and I found a similar reaction on a hair loss forum. anyone has this experience ?
It's also interesting to see that high Gaba function is found in prostate cancer and promotes cell proliferation.
Expression of gamma-aminobutyric acid receptor (subtype A) in prostate cancer. - PubMed - NCBI
Hair loss and prostate cancer go hand in hand. Englishmen also seem to have a higher percentage of balding men and they ingest a lot of theanine. Japan do too but in the form of green tea that is anti-androgenic and probably counteracts theanine's effect. This is only an hypothesis of course but I'd really be curious if people here have this experience.
I am in the middle of an extreme period of stress, and am feeling the effects physically and mentally. I would love to hear advice on managing my stress in such a way that I don't have to spend the next few years paying the price!
My husband has end stage cancer. He is paralyzed from the chest down, requiring diapers, being moved with a lift, etc. I am the primary caregiver, with occasional respites from family and hospice. I am not sleeping very much. I am physically exhausted. My diet is terrible, neither particularly nutritious nor pleasurable, as all he wants to eat are his childhood comfort foods: potato chips, pretzels, hot dogs, peanuts, doughnuts, and fortunately ice cream. In theory, I could make myself meals separate from his, but the reality is, I just don't have the energy to do it, so I end up eating the same crap as him. I have put on a lot of very uncomfortable weight around my middle, which is causing further stress! I am very bloated and gassy. I alternate between constipation and diarrhea. My nose is always blocked, causing me to breathe through my mouth most of the time. My teeth ache, my gums are receding and bleeding. i am having frequent migraines, shortness of breath, occasional back spasms, and feeling like I am going to faint when I am in public. Also, I am 50, and going through menopause.
I am taking Estroban, Pansterone, aspirin, ubiquinol, niacinimide, a lot of coffee (thank god for coffee). I love carrot salad, but usually just manage to eat a raw carrot while fixing supper.
Any ideas for me? I would love to mitigate the effects of this stressful time. Is there hope??
@Kim Many of my add symptoms has gone away in the last 2 weeks, and I think it is mainly because of taurine, theanine and glycine I take.
I don't take ritalin anymore. But for example, I'm for the first time in my life able to make habits, like brushing my teeth. You know, I would regularly brush my teeth, but it never felt like an habit to me, always I had to think about, and sometimes I would just forget.
Also, my sleep had been consistent, a bit late still, from 2 am to 10, but I can't remember a time that it had been so consistent.
My university work is so much organized, my work would be a chaotic mess. Even my handwriting has improved tremendously.
And so much more little things have changed, like for example, I put the cards of my wallet back in my wallet after I used them, I'm on time in my classes, I automatically make long term plans, I would never even think about what to do tomorrow, if I would not push myself.
Oh and I forget, my addictive behaviour has completely gone.